Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134481 | 0.87 | KMT2A (0.60) | MAPK1LMNAHTTRAB9A | |
| SCHEMBL18271231 | 0.83 | PTPN7 (0.56) | MAPK1LMNAHTTRAB9ASMYD3 | |
| SCHEMBL10144490 | 0.83 | HTR4 (0.61) | MAPK1SMYD3PTK2HTR4HPGDS | |
| SCHEMBL15761010 | 0.81 | EZH2 (0.53) | MAPK1RAB9ASMYD3HTR4HPGDS | |
| SCHEMBL16442371 | 0.81 | HTT (0.56) | MAPK1LMNAHTTRAB9AAKT1 | |
| Hydrochloric Acid SCHEMBL15758268 | 0.81 | EZH2 (0.52) | MAPK1RAB9ASMYD3HTR4HPGDS | |
| Hydrochloric Acid SCHEMBL16447312 | 0.80 | MEN1 (0.56) | MAPK1LMNAHTTRAB9AAKT1 | |
| SCHEMBL13575477 | 0.80 | HDAC6 (0.55) | RAB9ASMYD3HTR4TAS1R3TAS1R1 | |
| SCHEMBL13880649 | 0.80 | MAPK1 (0.58) | MAPK1SMYD3PTK2HTR4HPGDS | |
| SCHEMBL15761009 | 0.79 | EZH2 (0.50) | MAPK1RAB9ASMYD3PTK2HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156465-A1 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2009-06-18 | — | — | US | disclosed |
| EP-1973918-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES, LTD. (IN) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007077508-A2 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156465-A1 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | DPP4, DPP3, DPP7 | MAPK1 3046/4885LMNA 3069/4885HTT 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.