Malonic Acid

Malonic Acid

SCHEMBL4415530

CN(C)CCO.CN(C)CCO.O=C(O)CC(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.63
LDHA P00338 1/20 0.47
SRR Q9GZT4 1/20 0.47
KDM4A O75164 12/20 0.39
KDM4C Q9H3R0 12/20 0.39
KDM7A Q6ZMT4 2/20 0.39
PHF8 Q9UPP1 2/20 0.39
KDM2A Q9Y2K7 2/20 0.39
KDM5A P29375 1/20 0.39
PAOX Q6QHF9 1/20 0.36
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRM3 P20309 1/20 0.34
CHRNA4 P43681 1/20 0.34
DNM1 Q05193 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL4413840 1.00 MAPT (0.63) MAPTLDHASRRKDM4AKDM4C
Dimethylaminoethanol SCHEMBL357520 0.86 MAPT (0.67) MAPTKDM4AKDM4CKDM7APHF8
Dimethylaminoethanol SCHEMBL1131226 0.86 MAPT (0.75) MAPTKDM4AKDM4CKDM7APHF8
Dimethylaminoethanol SCHEMBL1131465 0.86 MAPT (0.75) MAPTKDM4AKDM4CKDM7APHF8
Succinic Acid SCHEMBL1131543 0.84 MAPT (0.63) MAPTKDM4AKDM4CKDM7APHF8
Dimethylaminoethanol SCHEMBL357728 0.84 MAPT (0.63) MAPTKDM4AKDM4CKDM7APHF8
Succinic Acid SCHEMBL28356804 0.84 MAPT (0.63) MAPTKDM4AKDM4CKDM7APHF8
Malonic Acid SCHEMBL5547634 0.84 FFAR3 (0.48) MAPTKDM4AKDM4CKDM7APHF8
Dimethylaminoethanol SCHEMBL1131507 0.83 MAPT (0.71) MAPTPAOXCHRM2CHRM4CHRM5
Dimethylaminoethanol SCHEMBL358310 0.83 MAPT (0.71) MAPTKDM4AKDM4CKDM7APHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603527-B1 TERPENOID FRAGRANCE COMPONENTS STABILIZED WITH MALONIC ACID SALTS UNILEVER PLC (GB) 2009-02-04 EP disclosed
US-7179772-B2 Extended lathering pillow article for personal care UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2007-02-20 US disclosed
EP-1509190-B1 ODOR CONTROL IN AMINE SALT CONTAINING COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2006-03-08 EP disclosed
US-20050288208-A1 Extended lathering pillow article for personal care UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-12-29 US disclosed
EP-1603527-A1 TERPENOID FRAGRANCE COMPONENTS STABILIZED WITH MALONIC ACID SALTS UNILEVER PLC (GB) 2005-12-14 EP disclosed
EP-1509195-A1 SUNSCREEN COSMETIC COMPOSITIONS STORAGE STABILIZED WITH MALONATE SALTS UNILEVER PLC (GB) 2005-03-02 EP disclosed
EP-1509197-A1 COSMETIC COMPOSITIONS CONTAINING SALTS OF MALONIC ACID UNILEVER PLC (GB) 2005-03-02 EP disclosed
EP-1509190-A1 ODOR CONTROL IN AMINE SALT CONTAINING COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2005-03-02 EP disclosed
US-20040202689-A1 Terpenoid fragrance components stabilized with malonic acid salts UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-10-14 US disclosed
WO-2004082652-A1 TERPENOID FRAGRANCE COMPONENTS STABILIZED WITH MALONIC ACID SALTS UNILEVER PLC (GB) 2004-09-30 WO disclosed
US-20040185073-A1 Cosmetic compositions containing salts of malonic acid UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-09-23 US disclosed
US-20040185074-A1 Odor control in amine salt containing cosmetic compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-09-23 US disclosed
US-20040185015-A1 Sunscreen cosmetic compositions storage stabilized with malonate salts UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-09-23 US disclosed
WO-2003099238-A1 ODOR CONTROL IN AMINE SALT CONTAINING COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2003-12-04 WO disclosed
WO-2003099254-A1 COSMETIC COMPOSITIONS CONTAINING SALTS OF MALONIC ACID UNILEVER PLC (GB) 2003-12-04 WO disclosed
WO-2003099250-A1 SUNSCREEN COSMETIC COMPOSITIONS STORAGE STABILIZED WITH MALONATE SALTS UNILEVER PLC (GB) 2003-12-04 WO disclosed