Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420206 | 0.81 | F10 (0.46) | F10MAPTF2 | |
| SCHEMBL4425775 | 0.79 | F10 (0.50) | F10F2 | |
| SCHEMBL4416573 | 0.79 | F10 (0.51) | F10F2 | |
| SCHEMBL4425739 | 0.78 | F10 (0.52) | F10F2 | |
| SCHEMBL4422056 | 0.78 | F10 (0.48) | F10F2 | |
| SCHEMBL4424896 | 0.73 | F10 (0.77) | F10F2 | |
| SCHEMBL4412919 | 0.70 | F10 (0.65) | F10F2 | |
| SCHEMBL11170712 | 0.68 | PDE3B (0.64) | PDE3BPDE3AMAPTSMN1; SMN2 | |
| SCHEMBL11176102 | 0.68 | PDE3B (0.72) | PDE3BPDE3AMAPTSMN1; SMN2 | |
| SCHEMBL11169119 | 0.68 | PDE3B (0.63) | PDE3BPDE3AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628972-B1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-22 | — | — | EP | claimed |