Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414413 | 0.94 | F10 (0.49) | F10F2PLATKLK1 | |
| SCHEMBL4416573 | 0.91 | F10 (0.51) | F10F2PLATKLK1 | |
| SCHEMBL4425775 | 0.86 | F10 (0.50) | F10F2PLATKLK1 | |
| SCHEMBL4425739 | 0.82 | F10 (0.52) | F10F2 | |
| SCHEMBL4420206 | 0.81 | F10 (0.46) | F10F2PLATKLK1 | |
| SCHEMBL4415769 | 0.78 | F10 (0.48) | F10F2 | |
| SCHEMBL4415806 | 0.76 | F10 (0.51) | F10F2PLATKLK1 | |
| SCHEMBL4424896 | 0.75 | F10 (0.77) | F10F2KLK1 | |
| SCHEMBL4419134 | 0.74 | FLT3 (0.42) | F10FLT3 | |
| SCHEMBL4422077 | 0.73 | F10 (0.64) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628972-B1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-22 | — | — | EP | claimed |