SCHEMBL4415844

SCHEMBL4415844

N[C@]1(Cl)CCCC[C@]1(N)Cl.[Pt]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2395690 1.00
SCHEMBL4412549 1.00
SCHEMBL10597160 1.00
SCHEMBL2986913 0.96 TSHR (0.30)
SCHEMBL29636254 0.96 TSHR (0.30)
SCHEMBL16415850 0.96 TSHR (0.30)
SCHEMBL9792256 0.96 TSHR (0.30)
SCHEMBL11145456 0.92 TSHR (0.35)
SCHEMBL31139018 0.92 TSHR (0.35)
SCHEMBL30722276 0.92 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0154589-B1 NEW ANTINEOPLASTIC PLATINUM (IV) COMPLEXES US COMMERCE (US) 1989-08-09 EP claimed
US-10759820-B2 Proliferative disease treatment methods with phosphaplatin complexes OHIO UNIVERSITY (US) 2020-09-01 US disclosed
US-20190315789-A1 PROLIFERATIVE DISEASE TREATMENT METHODS WITH PHOSPHAPLATIN COMPLEXES OHIO UNIVERSITY (US) 2019-10-17 US disclosed
US-10385083-B2 Phosphaplatin complexes and methods for treatment of proliferative diseases using the phosphaplatin complexes OHIO UNIVERSITY (US) 2019-08-20 US disclosed
US-10364264-B2 Proliferative disease treatment methods with phosphaplatin complexes OHIO UNIVERSITY (US) 2019-07-30 US disclosed
US-20170327522-A1 PROLIFERATIVE DISEASE TREATMENT METHODS WITH PHOSPHAPLATIN COMPLEXES OHIO UNIVERSITY (US) 2017-11-16 US disclosed
US-20170327521-A1 PHOSPHAPLATIN COMPLEXES AND METHODS FOR TREATMENT OF PROLIFERATIVE DISEASES USING THE PHOSPHAPLATIN COMPLEXES OHIO UNIVERSITY (US) 2017-11-16 US disclosed
US-9688709-B2 Phosphaplatins and their use for treatment of cancers OHIO UNIVERSITY (US) 2017-06-27 US disclosed
EP-2575802-B1 PHOSPHAPLATINS AND THEIR USE FOR TREATMENT OF CANCERS UNIV OHIO (US) 2016-11-16 EP disclosed
EP-2763537-A1 EFFICIENT PROCESSES FOR LARGE SCALE PREPARATION OF PHOSPHAPLATINS ANTITUMOR AGENTS Bose, Rathindra, N. (US) 2014-08-13 EP disclosed
EP-1749015-A1 A PROCESS FOR THE PREPARATION OF AN ANTI-TUMOR PLATINUM(II)-COMPLEX DABUR PHARMA LTD. (IN) 2007-02-07 EP disclosed
WO-2005075489-A1 A PROCESS FOR THE PERPARATION OF AN ANTI-TUMOR PLATINUM (II) - COMPLEX DABUR PHARMA LIMITED (IN) 2005-08-18 WO disclosed
US-5750716-A Method of producing platinum (II) complex TORAY INDUSTRIES, INC. (JP) 1998-05-12 US disclosed
EP-0768315-A1 PROCESS FOR THE PRODUCTION OF PLATINUM (II) COMPLEXES TORAY INDUSTRIES, INC. (JP) 1997-04-16 EP disclosed
US-5130450-A Amine or ammonia containing platinum complexes as antitumor agents, also containing carboxy or hydroxy groups NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1992-07-14 US disclosed
EP-0454042-A2 Novel platinum complexes Nippon Kayaku Kabushiki Kaisha (JP) 1991-10-30 EP disclosed
US-4739087-A ANTITUMOR AGENTS BRISTOL-MYERS COMPANY (US) 1988-04-19 US disclosed
US-4680308-A ANTITUMOR, ANTIINFLAMMATORY AND TRYPANOCIDAL AGENTS ANDRULIS RESEARCH CORPORATION (US) 1987-07-14 US disclosed
US-4599352-A TETRAHALO(1,2-DIAMINOCYCLOHEXANE) PLATINUM THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1986-07-08 US disclosed
US-4550187-A Synthesis of platinum (IV) antineoplastic agents THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1985-10-29 US disclosed