SCHEMBL9792256

SCHEMBL9792256

N[C@]1(Cl)CCCC[C@@]1(N)Cl

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16415850 1.00 TSHR (0.30) TSHRCYP2C19
SCHEMBL29636254 1.00 TSHR (0.30) TSHRCYP2C19
SCHEMBL2986913 1.00 TSHR (0.30) TSHRCYP2C19
SCHEMBL2395690 0.96
SCHEMBL4412549 0.96
SCHEMBL30615700 0.96 TSHR (0.35) TSHRCYP2C19
SCHEMBL31139018 0.96 TSHR (0.35) TSHRCYP2C19
SCHEMBL4415844 0.96
SCHEMBL11145456 0.96 TSHR (0.35) TSHRCYP2C19
SCHEMBL10597160 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0154589-B1 NEW ANTINEOPLASTIC PLATINUM (IV) COMPLEXES US COMMERCE (US) 1989-08-09 EP claimed
US-4376782-A ANTITUMOR AGENTS RESEARCH CORPORATION (US) 1983-03-15 US claimed
EP-0039272-A2 Platinum-isocitrate complex, process for its preparation and its therapeutical application ELF SANOFI (FR) 1981-11-04 EP claimed
US-5041579-A With cis-diamino cyclohexanol, nontoxic anti-tumor agent AJINOMOTO CO., INC. (JP) 1991-08-20 US disclosed
EP-0310260-A2 Platinum complexes and their use as anti-tumor agents AJINOMOTO CO., INC. (JP) 1989-04-05 EP disclosed
US-4376782-A ANTITUMOR AGENTS RESEARCH CORPORATION (US) 1983-03-15 US disclosed
US-4283342-A REACTION PRODUCT OF A HYDROXYQUINONE AND A CIS-PLATINUM COMPOUND UNIVERSITY OF DELAWARE (US) 1981-08-11 US disclosed