SCHEMBL4415869

SCHEMBL4415869

CC(C)C(=O)OC(c1ccc(C(=O)C(C)(C)O)cc1)c1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.38
MLYCD O95822 3/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
KIF11 P52732 1/20 0.31
NR1H4 Q96RI1 1/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2D6 P10635 1/20 0.31
HIF1A Q16665 1/20 0.31
SRC P12931 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL480464 0.83 ESR1 (0.51) ELANEESR1ESR2CA2CA12
SCHEMBL4418991 0.83 ELANE (0.37) ELANEMLYCDESR1ESR2CA2
SCHEMBL4418465 0.81 MLYCD (0.36) ELANEMLYCDESR1ESR2CA2
SCHEMBL10067693 0.81 ESR1 (0.45) ELANEMLYCDESR1ESR2CA2
SCHEMBL4425744 0.80 MLYCD (0.37) ELANEMLYCDCA2CA12CA1
SCHEMBL3088741 0.80 SRC (0.37) ELANEMLYCDESR1ESR2CA2
Methoxymethane SCHEMBL4418025 0.78 SRC (0.36) ELANEMLYCDESR1ESR2CA2
SCHEMBL15648878 0.77 ESR1 (0.42) ESR1ESR2SRCALDH1A1MAPT
SCHEMBL10067694 0.77 ESR1 (0.45) ELANEESR1ESR2CA2CA12
SCHEMBL54909 0.77 CYP2C9 (0.50) CYP2C9CYP2D6HIF1AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620475-B1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2009-11-11 EP disclosed
US-7462650-B2 Trifunctional photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-12-09 US disclosed
US-20060270748-A1 Novel trifunctional photoinitiators IGM GROUP B.V. (NL) 2006-11-30 US disclosed
EP-1620475-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS Ciba SC Holding AG (CH) 2006-02-01 EP disclosed
WO-2004099262-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-11-18 WO disclosed