Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327671 | 1.00 | CCR2 (0.73) | CCR2KCNH2 | |
| SCHEMBL4327667 | 0.92 | CCR2 (0.67) | CCR2KCNH2 | |
| SCHEMBL4331688 | 0.91 | CCR2 (0.69) | CCR2KCNH2 | |
| SCHEMBL4565870 | 0.91 | CCR2 (0.69) | CCR2KCNH2 | |
| Pf-4136309 SCHEMBL1377713 | 0.84 | CCR2 (1.00) | CCR2KCNH2 | |
| Pf-4136309 SCHEMBL13613003 | 0.84 | CCR2 (1.00) | CCR2KCNH2 | |
| SCHEMBL13627029 | 0.82 | CCR2 (0.52) | CCR2KCNH2 | |
| SCHEMBL1378000 | 0.81 | CCR2 (0.90) | CCR2KCNH2 | |
| SCHEMBL4425772 | 0.81 | CCR2 (0.90) | CCR2KCNH2 | |
| SCHEMBL4414421 | 0.81 | CCR2 (0.94) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576089-B2 | 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORPORATION | 2009-08-18 | — | — | US | disclosed |
| EP-1696919-A4 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-1696919-A2 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | Incyte Corporation (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005060665-A2 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |