Itaconate

Itaconate

SCHEMBL4416065

C=C(CC(=O)O)C(=O)O.C=C(CC(=O)O)C(=O)OC(=O)C(=C)CC(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.58
HSD17B10 Q99714 1/20 0.58
LDHA P00338 1/20 0.36
SRR Q9GZT4 1/20 0.36
TET2 Q6N021 4/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25232 0.93 ALOX15 (0.46) ALOX15HSD17B10LDHASRR
SCHEMBL27462226 0.90 ALOX15 (0.44) ALOX15HSD17B10LDHASRR
Glycolic Acid SCHEMBL11856868 0.86 ALOX15 (0.41) ALOX15HSD17B10LDHASRR
Itaconate SCHEMBL21523 0.84
Itaconate SCHEMBL29886131 0.84
Itaconate SCHEMBL286967 0.84 ALOX15 (0.75) ALOX15HSD17B10LDHASRRTET2
SCHEMBL4416067 0.84 ALOX15 (0.40) ALOX15HSD17B10LDHASRR
Itaconate SCHEMBL10984219 0.84 ALOX15 (0.56) ALOX15HSD17B10LDHASRRTET2
SCHEMBL31563653 0.83 ALOX15 (0.43) ALOX15HSD17B10LDHASRR
Acrylic Acid SCHEMBL17181086 0.82 ALOX15 (0.65) ALOX15HSD17B10LDHASRRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4016330-A Water-soluble wire enamel SCHENECTADY CHEMICALS, INC. (US) 1977-04-05 US claimed
US-3974115-A TRIBASIC ACID, DICARBOXYLIC ACID, POLYESTER, ORGANIC TITANATE SCHENECTADY CHEMICALS, INC. (US) 1976-08-10 US claimed
CN-114133560-B Process for the preparation of semiaromatic polyamides with improved impact strength, semiaromatic polyamides and moulding compositions 山东广垠新材料有限公司 2024-03-08 CN disclosed
CN-114058009-B Process for the preparation of semi-aromatic polyamides with reduced diamine monomer loss, semi-aromatic polyamides and molding compositions 山东广垠新材料有限公司 2023-11-10 CN disclosed
US-9688804-B2 Polymeric beads, process and composition DSM IP ASSETS B.V. (NL) 2017-06-27 US disclosed
EP-1737936-B1 HYDRAULIC COMPOSITION CONTAINING A SUBSTANTIALLY NITROGEN FREE DISPERSANT LUBRIZOL CORP (US) 2017-01-25 EP disclosed
US-9255171-B2 Polymer, process and composition DSM IP ASSETS B.V. (NL) 2016-02-09 US disclosed
US-20150010863-A1 USE OF A POLYMER COMPOSITION DSM IP ASSETS B.V. (NL) 2015-01-08 US disclosed
US-20150005442-A1 POLYMER, PROCESS AND COMPOSITION DSM IP ASSETS B.V. (NL) 2015-01-01 US disclosed
US-20140377464-A1 POLYMERIC BEADS, PROCESS AND COMPOSITION COVESTRO (NETHERLANDS) B.V. (NL) 2014-12-25 US disclosed
EP-2809720-A1 USE OF A POLYMER COMPOSITION DSM IP Assets B.V. (NL) 2014-12-10 EP disclosed
EP-1737936-A1 HYDRAULIC COMPOSITION CONTAINING A SUBSTANTIALLY NITROGEN FREE DISPERSANT THE LUBRIZOL CORPORATION (US) 2007-01-03 EP disclosed
WO-2005090530-A1 HYDRAULIC COMPOSITION CONTAINING A SUBSTANTIALLY NITROGEN FREE DISPERSANT THE LUBRIZOL CORPORATION (US) 2005-09-29 WO disclosed
US-20050209112-A1 Hydraulic composition containing a substantially nitrogen free dispersant THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO (US) 2005-09-22 US disclosed
EP-0897943-B1 Composite resin composition MITSUI CHEMICALS INC (JP) 2005-05-04 EP disclosed
EP-1011030-B1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2002-04-17 EP disclosed
US-6150438-A HEATING AND REACTING AN ALIPHATIC POLYESTER RESIN WITH HYDROXYCARBOXYLIC ACID UNITS AND UNSATURATED CARBOXYLIC ACID TO FORM A MODIFIED ALIPHATIC POLYESTER, KNEADING AND BONDING WITH A BIOMASS SELECTED FROM CELLULOSE, LIGNOCELLULOSE MITSUI CHEMICALS, INC. (JP) 2000-11-21 US disclosed
US-6124384-A Composite resin composition MITSUI CHEMICALS, INC. (JP) 2000-09-26 US disclosed
EP-1011030-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2000-06-21 EP disclosed
EP-0897943-A2 Composite resin composition Mitsui Chemicals, Inc. (JP) 1999-02-24 EP disclosed