Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613238 | 1.00 | SLC6A2 (0.30) | SLC6A2SLC6A4ATMBACE1 | |
| SCHEMBL611458 | 1.00 | SLC6A2 (0.30) | SLC6A2SLC6A4ATMBACE1 | |
| SCHEMBL8806529 | 1.00 | SLC6A2 (0.30) | SLC6A2SLC6A4ATMBACE1 | |
| SCHEMBL612895 | 1.00 | SLC6A2 (0.30) | SLC6A2SLC6A4ATMBACE1 | |
| SCHEMBL611459 | 1.00 | SLC6A2 (0.30) | SLC6A2SLC6A4ATMBACE1 | |
| SCHEMBL612894 | 1.00 | SLC6A2 (0.30) | SLC6A2SLC6A4ATMBACE1 | |
| SCHEMBL613239 | 1.00 | SLC6A2 (0.30) | SLC6A2SLC6A4ATMBACE1 | |
| SCHEMBL15478443 | 0.84 | MTNR1A (0.32) | SLC6A2SLC6A4ATM | |
| SCHEMBL3134859 | 0.82 | ITGB1 (0.32) | — | |
| SCHEMBL2150600 | 0.82 | MTNR1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076124-A2 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | Acucela, Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008131368-A2 | STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. (US) | 2008-10-30 | — | — | WO | disclosed |