Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.37 |
| ▸ | PDE5A | O76074 | 4/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663172 | 0.86 | BRD4 (0.39) | BRD4MTNR1AMTNR1BPDE5ATP53 | |
| SCHEMBL30361112 | 0.86 | BRD4 (0.39) | BRD4MTNR1AMTNR1BPDE5ATP53 | |
| SCHEMBL4408527 | 0.83 | MTNR1A (0.37) | BRD4MTNR1AMTNR1BPDE5ATP53 | |
| SCHEMBL4406896 | 0.82 | MTNR1A (0.33) | BRD4MTNR1AMTNR1BPDE5ATP53 | |
| SCHEMBL1666066 | 0.82 | MTNR1A (0.37) | BRD4MTNR1AMTNR1B | |
| SCHEMBL661152 | 0.81 | BRD4 (0.37) | BRD4MTNR1AMTNR1BPDE5ACYP11B1 | |
| SCHEMBL4406363 | 0.81 | BRD4 (0.37) | BRD4MTNR1AMTNR1BPDE5ACYP11B1 | |
| SCHEMBL661457 | 0.81 | PPARG (0.39) | MTNR1AMTNR1B | |
| SCHEMBL30361134 | 0.81 | PPARG (0.39) | MTNR1AMTNR1B | |
| SCHEMBL662088 | 0.80 | S1PR1 (0.40) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050736-A1 | Imidazole derivatives, processes for preparing them and their uses | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | disclosed |