Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415296 | 0.89 | CCR2 (0.69) | CCR2KCNH2CCR5 | |
| SCHEMBL4417175 | 0.86 | CCR2 (0.68) | CCR2KCNH2CCR5 | |
| SCHEMBL4416647 | 0.83 | CCR2 (0.52) | CCR2KCNH2CCR5 | |
| SCHEMBL4427345 | 0.82 | CCR2 (0.55) | CCR2KCNH2CCR5 | |
| SCHEMBL4413656 | 0.79 | CCR2 (0.78) | CCR2KCNH2CCR5 | |
| SCHEMBL4417195 | 0.79 | CCR2 (0.78) | CCR2KCNH2CCR5 | |
| SCHEMBL5553802 | 0.79 | CCR2 (0.70) | CCR2KCNH2CCR5 | |
| SCHEMBL4417177 | 0.78 | CCR2 (0.87) | CCR2KCNH2CCR5 | |
| SCHEMBL4417182 | 0.78 | CCR2 (0.87) | CCR2KCNH2CCR5 | |
| SCHEMBL4420786 | 0.77 | CCR2 (0.64) | CCR2KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606255-B1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2009-11-11 | — | — | EP | claimed |