SCHEMBL4416877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4273698	0.94	PDE4B (0.44)	PDE4BPDE4APDE4CPDE4DFPR2
	SCHEMBL4271738	0.94	PDE4B (0.47)	PDE4BPDE4APDE4CPDE4DFPR2
	SCHEMBL15711397	0.92	HCRTR1 (0.37)	PDE4BPDE4APDE4CPDE4DADORA2A
	SCHEMBL4279514	0.90	PDE4B (0.42)	PDE4BPDE4APDE4CPDE4DFPR2
	SCHEMBL4284444	0.89	PDE4B (0.43)	PDE4BPDE4APDE4CPDE4DFPR2
	SCHEMBL4278639	0.89	PDE4B (0.48)	PDE4BPDE4APDE4CPDE4DFPR2
	SCHEMBL4275019	0.89	PDE4A (0.43)	PDE4BPDE4APDE4CPDE4DFPR2
	SCHEMBL4285870	0.89	PDE4A (0.43)	PDE4BPDE4APDE4CPDE4DFPR2
	SCHEMBL4280788	0.87	PDE4B (0.47)	PDE4BPDE4APDE4CPDE4DALDH1A1
	SCHEMBL4284416	0.84	PDE4B (0.46)	PDE4BPDE4APDE4CPDE4DFPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.