Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.74 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074154 | 0.93 | HTR7 (0.87) | HTR7HTR1AHTR2AMEN1KMT2A | |
| SCHEMBL10804601 | 0.92 | HTR7 (0.86) | HTR7HTR1AHTR2AMEN1KMT2A | |
| SCHEMBL2076759 | 0.86 | HTR7 (0.76) | HTR7HTR1AHTR2A | |
| SCHEMBL28243922 | 0.85 | HTR7 (0.67) | HTR7HTR1AHTR2AMEN1KMT2A | |
| SCHEMBL10801116 | 0.84 | HTR7 (0.80) | HTR7HTR1AHTR2AKCNK3 | |
| SCHEMBL10803888 | 0.84 | HTR7 (0.80) | HTR7HTR1AHTR2A | |
| SCHEMBL2075429 | 0.83 | HTR7 (0.85) | HTR7HTR1AHTR2AMEN1KMT2A | |
| SCHEMBL2073608 | 0.81 | HTR7 (0.69) | HTR7HTR1AHTR2A | |
| SCHEMBL10806267 | 0.81 | HTR7 (0.76) | HTR7HTR1AHTR2A | |
| SCHEMBL2076086 | 0.81 | HTR7 (0.69) | HTR7HTR1AHTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668014-B1 | FUSED HETEROCYCLIC COMPOUNDS AS SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-01-14 | — | — | EP | claimed |