Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | GLA | P06280 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12408902 | 0.91 | KDM4E (0.70) | KDM4ESMN1; SMN2GLAGAAMAPT | |
| SCHEMBL27404431 | 0.88 | KDM4E (0.57) | KDM4ESMN1; SMN2GLAGAAMAPT | |
| SCHEMBL26745535 | 0.88 | APP (0.47) | KDM4ESMN1; SMN2GLAGAAMAPT | |
| SCHEMBL25811197 | 0.85 | KDM4E (0.52) | KDM4ESMN1; SMN2GLAGAAMAPT | |
| SCHEMBL26744933 | 0.84 | SMN1; SMN2 (0.50) | KDM4ESMN1; SMN2GLAGAAMAPT | |
| SCHEMBL13241705 | 0.84 | KDM4E (0.49) | KDM4ESMN1; SMN2GLAGAAMAPT | |
| SCHEMBL18999534 | 0.84 | KDM4E (0.49) | KDM4ESMN1; SMN2GLAGAAMAPT | |
| SCHEMBL29939237 | 0.83 | MAPT (0.79) | KDM4ESMN1; SMN2GLAGAAMAPT | |
| SCHEMBL31319825 | 0.83 | MAPT (0.79) | KDM4ESMN1; SMN2GLAGAAMAPT | |
| SCHEMBL30727497 | 0.83 | APP (0.62) | KDM4ESMN1; SMN2GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129738-A1 | THIAZOLE SYSTEM ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | Gracel Display Inc. (KR) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008117976-A1 | THIAZOLE SYSTEM ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | GRACEL DISPLAY INC. (KR) | 2008-10-02 | — | — | WO | disclosed |