SCHEMBL12408902

SCHEMBL12408902

c1ccc(-c2ccc3nc(-c4ccc(-c5nc6ccc(-c7ccccc7)cc6s5)cc4)sc3c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.70
MAPT P10636 6/20 0.70
GLA P06280 5/20 0.70
GAA P10253 5/20 0.70
SMN1; SMN2 Q16637 4/20 0.70
ALDH1A1 P00352 3/20 0.70
PKM P14618 2/20 0.70
HPGD P15428 2/20 0.70
MEN1 O00255 1/20 0.70
KMT2A Q03164 1/20 0.70
PIK3CA P42336 1/20 0.67
PI4KA P42356 1/20 0.67
PI4KB Q9UBF8 1/20 0.67
LMNA P02545 2/20 0.66
NFKB1 P19838 1/20 0.66
NFKB2 Q00653 1/20 0.66
RELA Q04206 1/20 0.66
APP P05067 10/20 0.64
NPC1 O15118 4/20 0.59
RAB9A P51151 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29939237 0.92 MAPT (0.79) KDM4EMAPTGLAGAASMN1; SMN2
SCHEMBL30727497 0.92 APP (0.62) KDM4EMAPTGLAGAASMN1; SMN2
SCHEMBL27001616 0.92 MAPT (0.79) KDM4EMAPTGLAGAASMN1; SMN2
SCHEMBL31319825 0.92 MAPT (0.79) KDM4EMAPTGLAGAASMN1; SMN2
SCHEMBL4417420 0.91 KDM4E (0.59) KDM4EMAPTGLAGAASMN1; SMN2
SCHEMBL13241670 0.91 KDM4E (0.59) KDM4EMAPTGLAGAASMN1; SMN2
SCHEMBL5593469 0.90 MAPT (0.69) KDM4EMAPTGLAGAASMN1; SMN2
SCHEMBL13241680 0.89 KDM4E (0.57) KDM4EMAPTGLAGAASMN1; SMN2
SCHEMBL27049206 0.88 KDM4E (0.65) KDM4EMAPTGLAGAASMN1; SMN2
SCHEMBL2999874 0.88 KDM4E (0.57) KDM4EMAPTGLAGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7973168-B2 Metallic compound and organic electroluminescence device comprising the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-07-05 US disclosed
US-7973168-B2 Metallic compound and organic electroluminescence device comprising the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-07-05 US disclosed
US-20090326236-A1 METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2009-12-31 US disclosed
US-20090326236-A1 METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2009-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326236-A1 METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME MT-CO1, ROS1, MAL2 KDM4E 2620/4885MAPT 2328/4885GLA 4028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.