Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL4131682 | 0.90 | KDM4E (0.46) | ACHEBCHE | |
| Dimethylamine SCHEMBL4114208 | 0.88 | ACHE (0.49) | ACHEBCHE | |
| Dimethylamine SCHEMBL4126994 | 0.87 | ACHE (0.40) | ACHEBCHE | |
| Dimethylamine SCHEMBL4121726 | 0.86 | ACHE (0.42) | ACHEBCHE | |
| Dimethylamine SCHEMBL4121165 | 0.86 | ACHE (0.44) | ACHEBCHE | |
| SCHEMBL4114424 | 0.86 | ACHE (0.47) | ACHEBCHE | |
| SCHEMBL4120426 | 0.85 | ACHE (0.46) | ACHEBCHE | |
| Dimethylamine SCHEMBL4127224 | 0.85 | ACHE (0.40) | ACHEBCHE | |
| Dimethylamine SCHEMBL4125717 | 0.85 | ACHE (0.41) | ACHEBCHE | |
| Dimethylamine SCHEMBL4121108 | 0.84 | ACHE (0.41) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ACHE 3716/4885BCHE 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.