SCHEMBL441863

SCHEMBL441863

CCC(N=C=O)OC(CC)N=C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5248815 0.82
SCHEMBL7258991 0.80
SCHEMBL5443738 0.80
SCHEMBL23797182 0.80 TSHR (0.30)
SCHEMBL9468035 0.80
SCHEMBL8755181 0.78
SCHEMBL11129173 0.78
SCHEMBL16949968 0.77 CA2 (0.31)
SCHEMBL23797149 0.77
SCHEMBL8485976 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020045723-A1 PROCESS FOR THE PRODUCTION OF ETHER ISOCYANATES BACKGROUND OF THE INVENTION BAYER AKTIENGESELLSCHAFT (DE) 2002-04-18 US claimed
EP-0764633-B1 Process for the preparation of etherisocyanates BAYER AG (DE) 2001-01-03 EP claimed
EP-0764633-A2 Process for the preparation of etherisocyanates BAYER AG (DE) 1997-03-26 EP claimed
US-11667768-B2 Polyisocyanate compositions VENCOREX FRANCE (FR) 2023-06-06 US disclosed
US-20230086342-A1 USE OF SPECIFIC OPEN-CHAIN ETHER ISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2023-03-23 US disclosed
EP-4118161-A1 USE OF SPECIFIC OPEN-CHAIN ETHER ISOCYANATES Covestro Deutschland AG (DE) 2023-01-18 EP disclosed
US-11168192-B2 Foamable polyamide composition and foam obtained therefrom BASF SE (DE) 2021-11-09 US disclosed
WO-2021180709-A1 USE OF SPECIFIC OPEN-CHAIN ETHER ISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2021-09-16 WO disclosed
EP-3878914-A1 USE OF SPECIFIC OPEN-CHAIN ETHER ISOCYANATES Covestro Deutschland AG (DE) 2021-09-15 EP disclosed
US-20200399439-A1 NEW POLYISOCYANATE COMPOSITIONS VENCOREX FRANCE (FR) 2020-12-24 US disclosed
US-10773276-B2 Method for forming multilayer coating film NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2020-09-15 US disclosed
WO-2008012281-A1 COMPOSITION THAT CAN BE POLYMERIZED AND/OR CROSSLINKED WHEN IRRADIATED BY CATIONIC AND/OR RADICAL ROUTE PERSTORP TOLONATES FRANCE (FR) 2008-01-31 WO disclosed
US-7297746-B2 Color stability of isocyanates RHODIA INC. (US) 2007-11-20 US disclosed
US-20060167124-A1 Expandable polyamide composition and polyamide foam obtained therefrom RHODIA POLYAMIDE INTERMEDIATES (FR) 2006-07-27 US disclosed
US-20050020766-A1 Color stability of isocyanates VENCOREX US, INC. 2005-01-27 US disclosed
US-20020045723-A1 PROCESS FOR THE PRODUCTION OF ETHER ISOCYANATES BACKGROUND OF THE INVENTION BAYER AKTIENGESELLSCHAFT (DE) 2002-04-18 US disclosed
US-6291577-B1 ADMIXING WITH POLYISOCYANATE A MOISTURE SCAVENGING COMPOUND SUCH AS 2,6-DITERTIARYBUTYL HYDROXYTOLUENE AND 2-TERTIARYBUTYL HYDROXYTOLUENE AND ALKYL ESTER TOLUENESULFONIC ACID AND SOLVENT RHODIA INC. 2001-09-18 US disclosed
EP-0764633-B1 Process for the preparation of etherisocyanates BAYER AG (DE) 2001-01-03 EP disclosed
EP-0764633-A2 Process for the preparation of etherisocyanates BAYER AG (DE) 1997-03-26 EP disclosed
EP-0764633-A2 Process for the preparation of etherisocyanates BAYER AG (DE) 1997-03-26 EP disclosed