Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.68 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.66 |
| ▸ | OSBP | P22059 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | RORC | P51449 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.62 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GBA1 | P04062 | 2/20 | 0.54 |
| ▸ | UGCG | Q16739 | 2/20 | 0.54 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14674808 | 1.00 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL14684819 | 1.00 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL28361659 | 1.00 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL4419195 | 1.00 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL11874094 | 0.93 | POLA1 (0.64) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL13885436 | 0.93 | POLA1 (0.64) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL11874091 | 0.93 | POLA1 (0.64) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL4432537 | 0.92 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL5888471 | 0.92 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL12695616 | 0.92 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111214701-A | Implants for localized drug delivery and methods of use thereof | 加利福尼亚大学董事会 | 2020-06-02 | — | — | CN | disclosed |
| CN-106573133-B | Implants for localized drug delivery and methods of use thereof | 加利福尼亚大学董事会 | 2020-03-03 | — | — | CN | disclosed |
| CN-106573133-A | Implants for localized drug delivery and methods of use thereof | 加利福尼亚大学董事会 | 2017-04-19 | — | — | CN | disclosed |
| WO-2015115589-A1 | HALOGEN ATOM-SUBSTITUTED POLYMERIZABLE COMPOUND | 日産化学工業株式会社 | 2015-08-06 | — | — | WO | disclosed |
| US-7514514-B2 | Photoactive copolymer | ROLIC AG (CH) | 2009-04-07 | — | — | US | disclosed |
| CN-1281644-C | Photoactive copolymer | ROLIC AG (CH) | 2006-10-25 | — | — | CN | disclosed |
| EP-1358234-B1 | PHOTOACTIVE COPOLYMER | ROLIC AG (CH) | 2006-06-28 | — | — | EP | disclosed |
| US-7022331-B2 | Thermochromic/photochromic cosmetic compositions | Theisen, Lyle (US) | 2006-04-04 | — | — | US | disclosed |
| US-20040138394-A1 | Photoactive copolymer | ROLIC AG (CH) | 2004-07-15 | — | — | US | disclosed |
| CN-1501948-A | Photoactive copolymer | — | 2004-06-02 | — | — | CN | disclosed |
| EP-1358234-A1 | PHOTOACTIVE COPOLYMER | Rolic AG (CH) | 2003-11-05 | — | — | EP | disclosed |
| US-20020192247-A1 | Thermochromic/photochromic cosmetic compositions | THEISEN LYLE (US) | 2002-12-19 | — | — | US | disclosed |
| WO-2002053609-A1 | PHOTOACTIVE COPOLYMER | ROLIC AG (CH) | 2002-07-11 | — | — | WO | disclosed |
| EP-1219651-A1 | Photoactive copolymer | Rolic AG (CH) | 2002-07-03 | — | — | EP | disclosed |
| US-4060910-A | Orientation system | GELL JR HAROLD A | 1977-12-06 | — | — | US | disclosed |