Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.68 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.66 |
| ▸ | OSBP | P22059 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | RORC | P51449 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.62 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.57 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GBA1 | P04062 | 2/20 | 0.54 |
| ▸ | UGCG | Q16739 | 2/20 | 0.54 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12695616 | 1.00 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL5888471 | 1.00 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL14674808 | 0.92 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL4419192 | 0.92 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL14684819 | 0.92 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL4419195 | 0.92 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL28361659 | 0.92 | POLA1 (0.68) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL18904679 | 0.92 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL14138204 | 0.92 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL11288161 | 0.92 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9204807-B2 | Devices for non-contact thermographic mapping of tissue for viability assessment and methods of their use | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2015-12-08 | — | — | US | claimed |
| US-20140236020-A1 | DEVICES FOR NON-CONTACT THERMOGRAPHIC MAPPING OF TISSUE FOR VIABILITY ASSESSMENT AND METHODS OF THEIR USE | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-08-21 | — | — | US | claimed |
| US-20080181928-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY | MIV THERAPEUTICS, INC. (CA) | 2008-07-31 | — | — | US | claimed |
| US-11918770-B2 | Implants for localized drug delivery and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-03-05 | — | — | US | disclosed |
| US-20220184362-A1 | Implants for Localized Drug Delivery and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-16 | — | — | US | disclosed |
| US-11324935-B2 | Implants for localized drug delivery and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-10 | — | — | US | disclosed |
| US-10912933-B2 | Implants for localized drug delivery and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-09 | — | — | US | disclosed |
| EP-3183026-B1 | IMPLANTS FOR LOCALIZED DRUG DELIVERY AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2019-10-30 | — | — | EP | disclosed |
| US-20190184145-A1 | Implants for Localized Drug Delivery and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-06-20 | — | — | US | disclosed |
| US-20170224970-A1 | Implants for Localized Drug Delivery and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-10 | — | — | US | disclosed |
| EP-3183026-A1 | IMPLANTS FOR LOCALIZED DRUG DELIVERY AND METHODS OF USE THEREOF | The Regents of The University of California (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2008077248-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY | MIV THERAPEUTICS INC. (CA) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008077247-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL | MIV THERAPEUTICS INC. (CA) | 2008-07-03 | — | — | WO | disclosed |
| US-7022331-B2 | Thermochromic/photochromic cosmetic compositions | Theisen, Lyle (US) | 2006-04-04 | — | — | US | disclosed |
| US-20020192247-A1 | Thermochromic/photochromic cosmetic compositions | THEISEN LYLE (US) | 2002-12-19 | — | — | US | disclosed |
| US-4999348-A | Sustained Release and Enhanced Penetration of Vitamin A | ESTEE LAUDER INC. (US) | 1991-03-12 | — | — | US | disclosed |
| US-4966205-A | Method and apparatus for charging transparent material | POLA CHEMICAL INDUSTRIES LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| US-4597942-A | LIQUID CRYSTALS | GRAPHIC CONTROLS CANADA LTD. (CA) | 1986-07-01 | — | — | US | disclosed |
| US-4383738-A | PLEOCHROIC DYE, OPTICALLY ACTIVE DOPANT | SHARP KABUSHIKI KAISHA (JP) | 1983-05-17 | — | — | US | disclosed |
| US-4060910-A | Orientation system | GELL JR HAROLD A | 1977-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181928-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY | LIPA, SGMS2, SGMS1 | POLA1 4883/4885CYP46A1 357/4885OSBP 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.