Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365678 | 0.81 | ACHE (0.38) | ACHECTSA | |
| SCHEMBL575309 | 0.80 | ACHE (0.33) | ACHECTSA | |
| SCHEMBL20644376 | 0.77 | CTSA (0.35) | ACHECTSA | |
| SCHEMBL30087321 | 0.76 | CTSA (0.32) | ACHECTSA | |
| SCHEMBL575965 | 0.75 | CTSA (0.39) | ACHECTSA | |
| SCHEMBL23060311 | 0.73 | ACHE (0.39) | ACHECTSA | |
| SCHEMBL4120026 | 0.72 | CTSA (0.31) | ACHECTSA | |
| SCHEMBL9961562 | 0.72 | ACHE (0.31) | ACHECTSA | |
| SCHEMBL575810 | 0.69 | — | — | |
| SCHEMBL9961564 | 0.69 | ACHE (0.33) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009544611-A | — | — | 2009-12-17 | — | — | JP | claimed |
| EP-2049124-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | Merck & Co., Inc. (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008010985-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2008-01-24 | — | — | WO | claimed |
| EP-2049124-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | Merck & Co., Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008010985-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2008-01-24 | — | — | WO | disclosed |