SCHEMBL4419477

SCHEMBL4419477

Fc1cccc(Oc2ccc(CN3CCCCC3)cc2)c1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
HRH3 Q9Y5N1 6/20 0.54
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51
CACNA1B Q00975 2/20 0.51
LTA4H P09960 1/20 0.50
HTT P42858 2/20 0.49
LMNA P02545 1/20 0.48
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
ACHE P22303 1/20 0.48
RAD52 P43351 1/20 0.48
MLNR O43193 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19206096 0.88 ALDH1A1 (0.71) ALDH1A1SMN1; SMN2HTTLMNAKDM4E
SCHEMBL19206074 0.84 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2CACNA1BLTA4HHTT
SCHEMBL6058205 0.83 HRH3 (0.75) ALDH1A1SMN1; SMN2HRH3CYP2D6CYP2C19
SCHEMBL6057447 0.83 HRH3 (0.75) ALDH1A1SMN1; SMN2HRH3CYP2D6CYP2C19
SCHEMBL6057466 0.81 HRH3 (0.71) ALDH1A1HRH3CYP2D6CYP2C19LTA4H
SCHEMBL6496864 0.79 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2HRH3HTTLMNA
SCHEMBL21347499 0.79 HRH3 (0.66) ALDH1A1SMN1; SMN2HRH3
SCHEMBL3168900 0.78 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2HRH3CYP2D6HTT
SCHEMBL29447405 0.78 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2HRH3CYP2D6HTT
SCHEMBL6499571 0.77 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2HTTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2032534-A1 4-[(3-FLUOROPHENOXY)PHENYLMETHYL]PIPERIDINE METHANESULFONATE: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS FAES FARMA, S.A. (ES) 2009-03-11 EP disclosed
WO-2007131846-A1 4-[(3-FLUOROPHENOXY)PHENYLMETHYL]PIPERIDINE METHANESULFONATE: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS FAES FARMA, S.A. (ES) 2007-11-22 WO disclosed