Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Adenosine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.66 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.66 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.74 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.74 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.74 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.74 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.74 |
| ▸ | SRC | P12931 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.74 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.71 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.70 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.70 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.70 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.70 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.69 |
| ▸ | QARS1 | P47897 | 1/20 | 0.68 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.66 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine Triphosphate SCHEMBL28794921 | 0.99 | P2RY1 (0.75) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| Adenosine Triphosphate SCHEMBL27722788 | 0.98 | P2RY1 (0.74) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| Adenosine Triphosphate SCHEMBL17107739 | 0.96 | P2RY1 (0.71) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| Adenosine Phosphate SCHEMBL15670584 | 0.92 | P2RY1 (0.78) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| Adenosine Triphosphate SCHEMBL28160534 | 0.91 | P2RY1 (0.79) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| Adenosine Triphosphate SCHEMBL3513897 | 0.91 | P2RY1 (0.63) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| Adenosine Triphosphate SCHEMBL5917790 | 0.90 | P2RY1 (0.80) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| Adenosine Triphosphate SCHEMBL29375927 | 0.90 | P2RY1 (0.93) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| Adenosine Triphosphate SCHEMBL7200593 | 0.90 | P2RY1 (0.93) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| Adenosine Triphosphate SCHEMBL13858121 | 0.90 | EZH2 (0.74) | P2RY1P2RY2P2RX1P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090162881-A1 | METHOD OF MEASURING ADENINE NUCLEOTIDE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2009-06-25 | — | — | US | disclosed |