⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423030 | 0.58 | — | — | |
| SCHEMBL715867 | 0.53 | GSK3B (1.00) | — | |
| SCHEMBL28900303 | 0.53 | — | — | |
| SCHEMBL10990 | 0.53 | — | — | |
| SCHEMBL11615305 | 0.53 | — | — | |
| SCHEMBL693917 | 0.53 | GSK3B (1.00) | — | |
| SCHEMBL7021498 | 0.53 | — | — | |
| SCHEMBL33524954 | 0.53 | — | — | |
| SCHEMBL1768562 | 0.51 | — | — | |
| Charcoal, Activated SCHEMBL4128314 | 0.51 | GSK3A (0.92) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3553 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337639-A1 | NAMPT INHIBITORS AND USES THEREOF | Remedy Plan, Inc. (US) | 2024-03-20 | — | — | EP | claimed |
| WO-2022241257-A1 | NAMPT INHBITORS AND USES THEREOF | REMEDY PLAN, INC. (US) | 2022-11-17 | — | — | WO | claimed |
| US-20210052548-A1 | MU OPIOID RECEPTOR MODULATORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | US | claimed |
| US-10702498-B2 | MU opioid receptor modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-07 | — | — | US | claimed |
| US-8217050-B2 | Adenine derivative as inhibitors of HSP90 for the treatment of cancer | CHROMA THERAPEUTICS LIMITED (GB) | 2012-07-10 | — | — | US | claimed |
| EP-2185567-B1 | SUBSTITUTED BICYCLOLACTAM COMPOUNDS | PFIZER PROD INC (US) | 2011-03-23 | — | — | EP | claimed |
| US-20100035901-A1 | ADENINE DERIVATIVE AS INHIBITORS OF HSP90 FOR THE TREATMENT OF CANCER | CHROMA THERAPEUTICS LTD. | 2010-02-11 | — | — | US | claimed |
| WO-2009136144-A1 | PURINE DERIVATIVES SUITABLE FOR THE TREATMENT OF CANCER, AUTOIMMUNE AND INFLAMMATORY DISEASES | CHROMA THERAPEUTICS LTD (GB) | 2009-11-12 | — | — | WO | claimed |
| EP-2084161-A1 | ADENINE DERIVATIVES AS INHIBITORS OF HSP90 FOR THE TREATMENT OF CANCER | Chroma Therapeutics Limited (GB) | 2009-08-05 | — | — | EP | claimed |
| JP-2009518459-A | — | — | 2009-05-07 | — | — | JP | claimed |
| EP-1948720-A1 | METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS | Alchimer (FR) | 2008-07-30 | — | — | EP | claimed |
| WO-2008056120-A1 | ADENINE DERIVATIVES AS INHIBITORS OF HSP90 FOR THE TREATMENT OF CANCER | CHROMA THERAPEUTICS LTD (GB) | 2008-05-15 | — | — | WO | claimed |
| WO-2007048894-A1 | METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS | ALCHIMER (FR) | 2007-05-03 | — | — | WO | claimed |
| JP-2000511883-A | — | — | 2000-09-12 | — | — | JP | claimed |
| WO-1997040017-A2 | MODULATORS OF MOLECULES WITH PHOSPHOTYROSINE RECOGNITION UNITS | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | claimed |
| EP-0069810-A1 | Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | claimed |
| US-12043607-B2 | HDAC inhibitors and therapeutic use thereof | TANGO THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043640-B2 | Prodrugs of STAT3 inhibitors | TVARDI THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| EP-0000978-B1 | 7-AND 8-SUBSTITUTED -10,11-DIHYDRO-11-OXODIBENZO (B,F) THIEPIN DERIVATIVES, THEIR PRODUCTION AND THEIR PARMACEUTICAL COMPOSITIONS | MERCK & CO. INC. (US) | 1982-09-15 | — | — | EP | disclosed |
| EP-0011067-B1 | PROSTAGLANDIN ANTAGONISTS, THEIR PRODUCTION AND THEIR PHARMACEUTICAL COMPOSITIONS | MERCK & CO. INC. (US) | 1982-04-21 | — | — | EP | disclosed |