SCHEMBL4419940

SCHEMBL4419940

COC(=O)C=Cc1ccc(OCCCCCCCCOc2cc(CO)cc(OCCCCCCCCOc3ccc(C=CC(=O)OC)cc3OC)c2)c(OC)c1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.70
ACHE P22303 11/20 0.55
BCHE P06276 6/20 0.55
APP P05067 2/20 0.53
KDM4E B2RXH2 1/20 0.52
EPHX2 P34913 1/20 0.51
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
NFE2L2 Q16236 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419931 1.00 FDPS (0.70) FDPSACHEBCHEAPPKDM4E
SCHEMBL4431021 0.91 FDPS (0.70) FDPSACHEBCHEAPPKDM4E
SCHEMBL4431018 0.91 FDPS (0.70) FDPSACHEBCHEAPPKDM4E
SCHEMBL6882597 0.89 FDPS (0.58) FDPSACHEBCHEAPPKDM4E
SCHEMBL6882602 0.89 FDPS (0.58) FDPSACHEBCHEAPPKDM4E
SCHEMBL6026728 0.89 FDPS (0.60) FDPSACHEBCHEAPPKDM4E
SCHEMBL6026736 0.89 FDPS (0.60) FDPSACHEBCHEAPPKDM4E
SCHEMBL6873896 0.86 FDPS (0.81) FDPSACHEBCHEAPPKDM4E
SCHEMBL6873903 0.86 FDPS (0.81) FDPSACHEBCHEAPPKDM4E
SCHEMBL13934765 0.86 FDPS (0.62) FDPSACHEBCHEAPPKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7491752-B2 Photoactive materials ROLIC AG (CH) 2009-02-17 US disclosed
US-7034098-B2 POlyimide, polyamide; liquid crystals, opticsoptics ROLIC AG (CH) 2006-04-25 US disclosed
EP-1368411-B1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2005-07-06 EP disclosed
US-20040265742-A1 Photoactive materials ROLIC AG (CH) 2004-12-30 US disclosed
US-20040185215-A1 Photoactive polymer based on polyimides, polyamic acids and esters characterised in that it contains as a side-chain a dendritic block incorporating photoactive groups at its surface; use as orientation layers for liquid crystals and in the construction of unstructured and structured optical elements ROLIC AG (CH) 2004-09-23 US disclosed
EP-1277770-A1 Photoactive materials Rolic AG (CH) 2003-01-22 EP disclosed
EP-1229066-A1 Photoactive polymer Rolic AG (CH) 2002-08-07 EP disclosed