Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961979 | 0.71 | — | — | |
| SCHEMBL4275827 | 0.62 | TSHR (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL5663155 | 0.61 | TSHR (0.32) | TSHR | |
| SCHEMBL100921 | 0.60 | — | — | |
| SCHEMBL276926 | 0.60 | — | — | |
| SCHEMBL1136405 | 0.60 | — | — | |
| SCHEMBL13873167 | 0.59 | TSHR (0.46) | TSHRSMN1; SMN2 | |
| SCHEMBL29280207 | 0.58 | — | — | |
| SCHEMBL7692466 | 0.58 | ADH1B (0.33) | TSHR | |
| SCHEMBL6953341 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312554-A1 | Novel Process for the Preparation of Hexacyclic Compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-12-17 | — | — | US | disclosed |
| EP-2106413-A1 | THERMALLY SENSITIVE POLYMERIC DYE TRANSFER INHIBITOR | BASF SE (DE) | 2009-10-07 | — | — | EP | disclosed |
| EP-1480984-B9 | HEXACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008077910-A1 | THERMALLY SENSITIVE POLYMERIC DYE TRANSFER INHIBITOR | BASF SE (DE) | 2008-07-03 | — | — | WO | disclosed |
| EP-1480984-B1 | CONDENSED CAMPTOTHECINS AS ANTITUMOR AGENTS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-06-11 | — | — | EP | disclosed |
| US-20060178376-A1 | Novel process for the preparation of hexacyclic compounds | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-08-10 | — | — | US | disclosed |
| US-6825194-B2 | AN 11,12-(-N=C(=O,S OR NH)-NH-)CAMPTOTHECIN DERIVATIVE OR AN 11,12-(-N=CH-NH-)CAMPTOTHEDIN DERIVATIVE; ANTICARCINOGENIC, -TUMOR AND -PROLIFERATIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0835248-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| EP-0628026-A1 | CYANO-OXIME ETHERS, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE. | BASF AG (DE) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993016985-A1 | CYANO-OXIME ETHERS, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-02 | — | — | WO | disclosed |
| WO-1993016033-A1 | CYCLOHEXENONE OXIME ETHERS, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-19 | — | — | WO | disclosed |
| EP-0091594-B1 | AMINOCARBOXYLIC ACID DERIVATIVES | Sanraku Incorporated (JP) | 1986-01-22 | — | — | EP | disclosed |
| US-4528397-A | Aminocarboxylic acid derivatives | SANRAKU-OCEAN CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |
| EP-0091594-A1 | Aminocarboxylic acid derivatives | Sanraku Incorporated (JP) | 1983-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178376-A1 | Novel process for the preparation of hexacyclic compounds | CYP11B1, CYP4A11, CYP51A1 | TSHR 1804/4885SMN1; SMN2 3908/4885 |
| US-20090312554-A1 | Novel Process for the Preparation of Hexacyclic Compounds | CYP11B1, CYP4A11, CYP51A1 | TSHR 1804/4885SMN1; SMN2 3908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.