Benzodiazepine

Benzodiazepine

SCHEMBL4420872

C1=Cc2ccccc2NN=C1.[Ag]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzodiazepine SCHEMBL7160172 0.98 GAA (0.44) GAAMAPT
Benzodiazepine SCHEMBL8137 0.98 GAA (0.44) GAAMAPT
Benzodiazepine SCHEMBL4700331 0.96 GAA (0.43) GAAMAPT
Benzodiazepine SCHEMBL11809777 0.96 GAA (0.43) GAAMAPT
Benzodiazepine SCHEMBL4144041 0.96 GAA (0.43) GAAMAPT
Benzodiazepine SCHEMBL11474576 0.96 GAA (0.43) GAAMAPT
Benzodiazepine SCHEMBL936208 0.96 GAA (0.43) GAAMAPT
Benzodiazepine SCHEMBL6618830 0.96 GAA (0.43) GAAMAPT
Benzodiazepine SCHEMBL11484022 0.96 GAA (0.43) GAAMAPT
Benzodiazepine SCHEMBL8139617 0.96 GAA (0.43) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10251392-B2 Antimicrobial devices and compositions AVENT, INC. (US) 2019-04-09 US disclosed
US-20090035342-A1 Antimicrobial Devices and Compositions AVANOS MEDICAL SALES, LLC 2009-02-05 US disclosed
EP-1781098-A2 ANTIMICROBIAL DEVICES AND COMPOSITIONS ACRYMED, INC. (US) 2007-05-09 EP disclosed
WO-2006015317-A2 ANTIMICROBIAL DEVICES AND COMPOSITIONS ACRYMED, INC. (US) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10251392-B2 Antimicrobial devices and compositions AAAS, AOC1, COL14A1 GAA 1128/4885MAPT 2314/4885
US-20090035342-A1 Antimicrobial Devices and Compositions AAAS, AOC1, COL14A1 GAA 1128/4885MAPT 2314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.