Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15903926 | 0.81 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8PYGL | |
| SCHEMBL29440834 | 0.81 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8PYGL | |
| SCHEMBL4420902 | 0.79 | ABCC9 (0.46) | ABCC9ABCC8KCNJ11KCNJ8PYGL | |
| SCHEMBL1573154 | 0.79 | ABCC9 (0.45) | ABCC9ABCC8KCNJ11KCNJ8PYGL | |
| SCHEMBL4497581 | 0.72 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8TSHR | |
| SCHEMBL1573133 | 0.71 | ABCC9 (0.40) | ABCC9ABCC8KCNJ11KCNJ8NR1H4 | |
| SCHEMBL7078236 | 0.70 | CYP1A2 (0.55) | ABCC9ABCC8KCNJ11KCNJ8PYGL | |
| SCHEMBL2552734 | 0.66 | TSHR (0.74) | TSHRNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29785065 | 0.66 | TSHR (0.74) | TSHRNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10632105 | 0.66 | CA12 (0.61) | PYGLTSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018165-A1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | Sanofi-Aventis (FR) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007080325-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI-AVENTIS (FR) | 2007-07-19 | — | — | WO | disclosed |