Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15610 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL4629242 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL6674757 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL8872228 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL8872482 | 1.00 | LMNA (0.50) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL3460324 | 0.99 | TSHR (0.49) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| Acetic Acid SCHEMBL28691928 | 0.97 | TSHR (0.48) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| Alcohol SCHEMBL27701846 | 0.97 | LMNA (0.48) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| Glycolic Acid SCHEMBL3845223 | 0.95 | LMNA (0.46) | LMNAALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL29696492 | 0.95 | TDP1 (0.46) | LMNAALDH1A1TSHRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370657-B2 | Treatment of Collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene | CURNA, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20170073680-A1 | TREATMENT OF COLLAGEN GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A COLLAGEN GENE | CURNA, INC. | 2017-03-16 | — | — | US | disclosed |
| EP-1187598-B1 | MICROPIGMENT MIXTURE | BASF SE (DE) | 2009-10-21 | — | — | EP | disclosed |