Benzimidazole

Benzimidazole

SCHEMBL442159

O=C(O)c1c(C(=O)O)c2c(C(=O)O)ccc3c4cccc5cccc(c(c1C(=O)O)c23)c54.c1ccc2[nH]cnc2c1.c1ccc2[nH]cnc2c1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.38
PARP1 P09874 1/20 0.38
CTNNB1 P35222 1/20 0.36
WNT3A P56704 1/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DYRK1A Q13627 1/20 0.34
MAPT P10636 3/20 0.34
CAMKK1 Q8N5S9 2/20 0.34
CAMKK2 Q96RR4 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CASP1 P29466 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzimidazole SCHEMBL2695888 1.00 PDE10A (0.38) PDE10APARP1CTNNB1WNT3AMEN1
Benzimidazole SCHEMBL27651909 0.99 PDE10A (0.38) PDE10APARP1CTNNB1WNT3AMEN1
Naphthalene SCHEMBL3478063 0.82 NR4A1 (0.46) PARP1MEN1KMT2AKDM4EALDH1A1
Benzimidazole SCHEMBL1353216 0.82 CTNNB1 (0.46) PDE10APARP1CTNNB1WNT3AKDM4E
SCHEMBL29450079 0.82 HSD17B10 (0.47) PARP1MEN1KMT2AKDM4EALDH1A1
SCHEMBL28062062 0.82 HSD17B10 (0.47) PARP1MEN1KMT2AKDM4EALDH1A1
SCHEMBL31542978 0.82 HSD17B10 (0.47) PARP1MEN1KMT2AKDM4EALDH1A1
SCHEMBL186130 0.82 HSD17B10 (0.47) PARP1MEN1KMT2AKDM4EALDH1A1
Benzimidazole SCHEMBL10625309 0.81 RAB9A (0.44) PARP1CTNNB1WNT3AMEN1KMT2A
Benzimidazole SCHEMBL36282 0.81 RAB9A (0.44) PARP1CTNNB1WNT3AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3751629-B1 ORGANIC PHOTOVOLTAIC CELL INCORPORATING ELECTRON CONDUCTING EXCITON BLOCKING LAYERS UNIV MICHIGAN REGENTS (US) 2024-05-01 EP claimed
EP-3751629-A1 ORGANIC PHOTOVOLTAIC CELL INCORPORATING ELECTRON CONDUCTING EXCITON BLOCKING LAYERS The Regents of the University of Michigan (US) 2020-12-16 EP claimed
US-9515273-B2 Thin film transistor with a current-induced channel INDIAN INSTITUTE OF TECHNOLOGY KANPUR (IN) 2016-12-06 US claimed
US-20150008420-A1 THIN FILM TRANSISTOR WITH A CURRENT-INDUCED CHANNEL EMPIRE TECHNOLOGY DEVELOPMENT LLC 2015-01-08 US claimed
WO-2014102625-A9 THIN FILM TRANSISTOR WITH A CURRENT-INDUCED CHANNEL INDIAN INSTITUTE OF TECHNOLOGY KANPUR (IN) 2014-09-12 WO claimed
US-8816332-B2 Organic photovoltaic cell incorporating electron conducting exciton blocking layers THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2014-08-26 US claimed
WO-2014102625-A1 THIN FILM TRANSISTOR WITH A CURRENT-INDUCED CHANNEL INDIAN INSTITUTE OF TECHNOLOGY KANPUR (IN) 2014-07-03 WO claimed
WO-2012161773-A1 ORGANIC PHOTOVOLTAIC CELL INCORPORATING ELECTRON CONDUCTING EXCITON BLOCKING LAYERS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2012-11-29 WO claimed
US-20120235125-A1 ORGANIC PHOTOVOLTAIC CELL INCORPORATING ELECTRON CONDUCTING EXCITON BLOCKING LAYERS UNITED STATES DEPARTMENT OF ENERGY 2012-09-20 US claimed
US-20090133752-A1 Organic Photovoltaic Device With Improved Power Conversion Efficiency And Method Of Manufacturing Same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-05-28 US claimed
US-20060249203-A1 Solar power module having carbon nanotubes INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2006-11-09 US claimed
US-7026019-B2 Anisotropic films based on 1,8-naphthoylene-1′,2′-benzimidazole sulfonates and lyotropic liquid crystal systems and methods for making NITTO DENKO CORPORATION (JP) 2006-04-11 US claimed
JP-4073973-A None JP disclosed
EP-3751629-B1 ORGANIC PHOTOVOLTAIC CELL INCORPORATING ELECTRON CONDUCTING EXCITON BLOCKING LAYERS UNIV MICHIGAN REGENTS (US) 2024-05-01 EP disclosed
EP-3411907-B1 MULTICOLOR ENERGY CONVERSION DEVICE, AND METHOD FOR THREE-DIMENSIONAL STRUCTURING OF THIN FILMS ARDEJE (FR) 2024-02-14 EP disclosed
WO-2023176829-A1 PHOTOVOLTAIC ELEMENT, OPTICAL SENSOR, IMAGING ELEMENT, AND FINGERPRINT AUTHENTICATION DEVICE 東レ株式会社 2023-09-21 WO disclosed
US-6657378-B2 Organic photovoltaic devices THE TRUSTEES OF PRINCETON UNIVERSITY 2003-12-02 US disclosed
US-20030042846-A1 Organic photovoltaic devices NATIONAL SCIENCE FOUNDATION 2003-03-06 US disclosed
WO-2002101838-A1 ORGANIC PHOTOVOLTAIC DEVICES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2002-12-19 WO disclosed
JP-H0473973-A ORGANIC SOLAR CELL AGENCY OF IND SCIENCE & TECHNOL 1992-03-09 JP disclosed