Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600750 | 0.83 | CCR1 (0.54) | CCR1CCR5CCR8NQO2PRMT5 | |
| SCHEMBL29847528 | 0.83 | CCR1 (0.54) | CCR1CCR5CCR8NQO2PRMT5 | |
| SCHEMBL731409 | 0.79 | HTT (0.40) | CCR1CCR5CCR8NQO2MEN1 | |
| SCHEMBL730007 | 0.79 | CCR1 (0.39) | NR4A2CCR1CCR5CCR8NQO2 | |
| SCHEMBL27185251 | 0.76 | EGFR (0.43) | NQO2NSD2CASP6ALDH1A1MAPT | |
| SCHEMBL439148 | 0.75 | NR4A2 (0.40) | NR4A2CCR1CCR5CCR8NSD2 | |
| SCHEMBL24532133 | 0.73 | KDM4E (0.46) | MEN1KMT2AALDH1A1MAPTPARP4 | |
| SCHEMBL29681293 | 0.73 | KDM4E (0.46) | MEN1KMT2AALDH1A1MAPTPARP4 | |
| SCHEMBL22715874 | 0.73 | PDE5A (0.44) | NQO2ALDH1A1MAPTPARP1PARP2 | |
| SCHEMBL442077 | 0.73 | NR4A2 (0.45) | NR4A2NQO2NCF1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |