Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.40 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10008628 | 0.79 | NR4A2 (0.56) | NR4A2SOS2MEN1KMT2AALDH1A1 | |
| SCHEMBL31392519 | 0.79 | KDM4E (0.39) | NR4A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4876537 | 0.76 | NSD2 (0.41) | ALDH1A1MAPTNSD2CASP6SMN1; SMN2 | |
| SCHEMBL442160 | 0.75 | NR4A2 (0.40) | NR4A2SOS2MEN1KMT2AAPAF1 | |
| SCHEMBL438506 | 0.73 | NR4A2 (0.44) | NR4A2SOS2MEN1KMT2AAPAF1 | |
| SCHEMBL438361 | 0.73 | ALDH1A1 (0.36) | KMT2AALDH1A1MAPTKDM4ENOS3 | |
| SCHEMBL442131 | 0.73 | NR4A2 (0.45) | NR4A2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL440408 | 0.72 | NR4A2 (0.61) | NR4A2MEN1KMT2AAPAF1TDP2 | |
| SCHEMBL437542 | 0.69 | KDM4E (0.33) | KMT2AALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL439581 | 0.68 | ACHE (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |