Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189773 | 0.84 | — | — | |
| SCHEMBL2904794 | 0.84 | — | — | |
| SCHEMBL796904 | 0.73 | HDAC8 (0.30) | — | |
| SCHEMBL789273 | 0.71 | — | — | |
| SCHEMBL15282895 | 0.67 | HSD11B1 (0.31) | — | |
| SCHEMBL31310637 | 0.67 | — | — | |
| SCHEMBL11788080 | 0.65 | TSHR (0.33) | ALDH1A1CASP1HSD17B10 | |
| SCHEMBL1137425 | 0.64 | MAPT (0.36) | — | |
| SCHEMBL11392187 | 0.64 | — | — | |
| SCHEMBL15209806 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035411-A1 | MUSCARINIC RECEPTOR AGONISTS THAT ARE EFFECTIVE IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA. | Astra Zeneca AB (SE) | 2009-03-18 | — | — | EP | claimed |
| WO-2007142583-A1 | MUSCARINIC RECEPTOR AGONISTS THAT ARE EFFECTIVE IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA. | ASTRAZENECA AB (SE) | 2007-12-13 | — | — | WO | claimed |
| US-6974815-B2 | Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-12-13 | — | — | US | disclosed |
| US-6974815-B2 | Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-12-13 | — | — | US | disclosed |
| US-20040116467-A1 | Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents | CEREP SA (FR) | 2004-06-17 | — | — | US | disclosed |
| US-20040116467-A1 | Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents | CEREP SA (FR) | 2004-06-17 | — | — | US | disclosed |
| WO-2004032861-A2 | HEXAHYDRO-BENZIMIDAZOLONE COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-22 | — | — | WO | disclosed |
| US-4411904-A | Diphenylpropanamines, compositions thereof and use thereof | WARNER-LAMBERT COMPANY (US) | 1983-10-25 | — | — | US | disclosed |
| US-4364954-A | NEUROLEPTIC AGENT | WARNER-LAMBERT COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| US-4292321-A | 1,3,8-Triazaspirodecane-4-ones, pharmaceutical compositions thereof and method of use thereof | WARNER-LAMBERT COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| US-3992401-A | MONOMERS FOR POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3939125-A | CURABLE | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |