SCHEMBL4422072

SCHEMBL4422072

CCCCCC=CC(=O)CCC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.70
PPARA Q07869 5/20 0.70
KDM4E B2RXH2 1/20 0.54
TERT O14746 3/20 0.53
PTPN1 P18031 3/20 0.53
PPARD Q03181 3/20 0.53
CYP1A2 P05177 2/20 0.53
MAPT P10636 2/20 0.53
CYP2C19 P33261 2/20 0.53
BLM P54132 2/20 0.53
HSD17B10 Q99714 2/20 0.53
FABP4 P15090 2/20 0.53
FAAH O00519 2/20 0.53
KMT2A Q03164 2/20 0.53
GMNN O75496 1/20 0.53
USP2 O75604 1/20 0.53
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
CYP2C9 P11712 1/20 0.53
ALOX15 P16050 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4422070 1.00 PPARG (0.70) PPARGPPARAKDM4ETERTPTPN1
Hydrochloric Acid SCHEMBL4419527 0.98 PPARG (0.68) PPARGPPARAKDM4ETERTPTPN1
Hydrochloric Acid SCHEMBL4419530 0.98 PPARG (0.68) PPARGPPARAKDM4ETERTPTPN1
SCHEMBL4952427 0.93 PPARG (0.61) PPARGPPARAKDM4ETERTPTPN1
SCHEMBL2599317 0.91 PPARG (0.82) PPARGPPARAKDM4ETERTPTPN1
SCHEMBL6192216 0.91 PPARG (0.76) PPARGPPARAKDM4ETERTPTPN1
SCHEMBL6448401 0.91 PPARG (0.82) PPARGPPARAKDM4ETERTPTPN1
SCHEMBL7939881 0.91 PPARG (0.76) PPARGPPARAKDM4ETERTPTPN1
SCHEMBL8593649 0.89 PPARG (0.86) PPARGPPARAKDM4ETERTPTPN1
SCHEMBL812752 0.89 PPARG (0.86) PPARGPPARAKDM4ETERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119837910-A Application of biota orientalis essential oil in fields of antioxidation and immunity enhancing medicines/foods 常州大学 2025-04-18 CN claimed
EP-2129224-B1 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS ANADYS PHARMACEUTICALS INC (US) 2016-03-30 EP claimed
EP-2718273-A1 [1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS FOR LOWERING SERUM URIC ACID Anadys Pharmaceuticals, Inc. (US) 2014-04-16 EP claimed
WO-2012170536-A1 [1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS FOR LOWERING SERUM URIC ACID ANADYS PHARMACEUTICALS, INC. (US) 2012-12-13 WO claimed
EP-2129224-A1 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS Anadys Pharmaceuticals, Inc. (US) 2009-12-09 EP claimed
WO-2008124450-A1 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS ANADYS PHARMACEUTICALS, INC. (US) 2008-10-16 WO claimed
CN-119837910-A Application of biota orientalis essential oil in fields of antioxidation and immunity enhancing medicines/foods 常州大学 2025-04-18 CN disclosed
CN-114073253-A Synergistic formulation for controlling and repelling biting arthropods 贝杜基昂研究股份有限公司 2022-02-22 CN disclosed
WO-2018140718-A1 FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS BEDOUKIAN RESEARCH, INC. (US) 2018-08-02 WO disclosed
EP-3068221-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS Bedoukian Research, Inc. (US) 2016-09-21 EP disclosed
EP-2129224-B1 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS ANADYS PHARMACEUTICALS INC (US) 2016-03-30 EP disclosed
WO-2015073671-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS BEDOUKIAN RESEARCH, INC. (US) 2015-05-21 WO disclosed
EP-2718273-A1 [1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS FOR LOWERING SERUM URIC ACID Anadys Pharmaceuticals, Inc. (US) 2014-04-16 EP disclosed
WO-2009152166-A1 [1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS ANADYS PHARMACEUTICALS, INC. (US) 2009-12-17 WO disclosed
US-20090306057-A1 [1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS ANADYS PHARMACEUTICALS, INC. (US) 2009-12-10 US disclosed
EP-2129224-A1 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS Anadys Pharmaceuticals, Inc. (US) 2009-12-09 EP disclosed
WO-2008144500-A2 1-METHYL-BENZO[1,2,4]THIADIAZINE, 1-OXIDE DERIVATIVES ANADYS PHARMACEUTICALS, INC. (US) 2008-11-27 WO disclosed
WO-2008124450-A1 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS ANADYS PHARMACEUTICALS, INC. (US) 2008-10-16 WO disclosed
EP-0719245-A1 NOVEL COMPOUNDS NOVO NORDISK A/S (DK) 1996-07-03 EP disclosed
WO-1995007878-A1 NOVEL COMPOUNDS NOVO NORDISK A/S (DK) 1995-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306057-A1 [1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS CYP2E1, CYP1A1, CYP1B1 PPARG 1586/4885PPARA 1932/4885KDM4E 2195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.