SCHEMBL4422088

SCHEMBL4422088

C=C(C)C(=O)O[NH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634428 0.75
SCHEMBL15963 0.73 ALDH1A1 (0.61)
SCHEMBL2215339 0.73 ALDH1A1 (0.61)
SCHEMBL28170047 0.73 ALDH1A1 (0.61)
SCHEMBL3977846 0.73 ALDH1A1 (0.52)
Hno SCHEMBL31285381 0.73
SCHEMBL1849 0.71
SCHEMBL179937 0.71
SCHEMBL8953021 0.71 ALDH1A1 (0.58)
Hydrochloric Acid SCHEMBL17099626 0.71 ALDH1A1 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090258966-A1 Dental Composition NIHON UNIVERSITY (JP) 2009-10-15 US disclosed
EP-1019416-B1 LOW WATER POLYMERIC SILICONE COMPOSITIONS HAVING REDUCED MODULUS BAUSCH & LOMB (US) 2003-01-22 EP disclosed
EP-0865444-B1 MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF SILICONE HYDROGELS BAUSCH & LOMB (US) 2001-09-19 EP disclosed
EP-1019416-A1 MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF LOW WATER POLYMERIC SILICONE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2000-07-19 EP disclosed
US-5908906-A ESPECIALLY POLYMERS FROM 1-(3-METHACRYLOYLOXYPROPYL)-3-(1,1H-PERFLUOROPENTYLOXY)PROPYL) TETRAMETHYLDISILOXANE, CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1999-06-01 US disclosed
EP-0865444-A1 MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF SILICONE HYDROGELS BAUSCH & LOMB INCORPORATED (US) 1998-09-23 EP disclosed
US-5714557-A UNSATURATED FLUORINATED ACRYLIC ESTER- OR AMIDE-CAPPED POLYSILOXANES AND DISILOXANES; CONTACT LENSES; FILMS; YOUNG'S MODULUS OF ELASTICIY; NONHYDROLYZING; MEDICAL EQUIPMENT BAUSCH & LOMB INCORPORATED (US) 1998-02-03 US disclosed
US-5710302-A Monomeric units useful for reducing the modules of silicone hydrogels BAUSCH & LOMB INCORPORATED (US) 1998-01-20 US disclosed
WO-1997020852-A1 MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF SILICONE HYDROGELS BAUSCH & LOMB INCORPORATED (US) 1997-06-12 WO disclosed
WO-1997020851-A1 MONOMERIC UNITS USEFUL FOR REDUCING THE MODULUS OF LOW WATER POLYMERIC SILICONE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 1997-06-12 WO disclosed