⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995930 | 0.74 | MAPT (0.48) | — | |
| SCHEMBL461605 | 0.73 | — | — | |
| SCHEMBL149587 | 0.73 | — | — | |
| Bromide SCHEMBL19681460 | 0.71 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL23960321 | 0.69 | — | — | |
| SCHEMBL7287966 | 0.69 | — | — | |
| SCHEMBL10609050 | 0.69 | — | — | |
| SCHEMBL1761114 | 0.69 | — | — | |
| SCHEMBL2301410 | 0.69 | — | — | |
| SCHEMBL6845014 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522945-C | Substituted 2-thio-3, 5-dicyano-4-phenyl-6-aminopyridines and use thereof | BAYER HEALTHCARE AG (DE) | 2009-08-05 | — | — | CN | disclosed |
| EP-1455785-B1 | SUBSTITUTED 2-THIO-3,5-DICYANO-4-PHENYL-6-AMINOPYRIDINES AND THE USE OF THE SAME | BAYER HEALTHCARE AG (DE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007073855-A1 | USE OF ADENOSINE A1 RECEPTOR AGONISTS FOR THE PROTECTION OF RENAL CELLS AGAINST TOXIC EFFECTS CAUSED BY AMINOGLYCOSIDES DURING TREATMENT OF INFECTIOUS DISEASES | BAYER HEALTHCARE AG (DE) | 2007-07-05 | — | — | WO | disclosed |
| US-20060217373-A1 | Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and the use of the same | BAYER HEALTHCARE AG (DE) | 2006-09-28 | — | — | US | disclosed |
| US-7109218-B2 | Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and the use of the same | BAYER HEALTHCARE AG (DE) | 2006-09-19 | — | — | US | disclosed |
| US-20050227972-A1 | Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and the use of the same | BAYER HEALTHCARE AG (DE) | 2005-10-13 | — | — | US | disclosed |
| CN-1617721-A | Substituted 2-thio-3, 5-dicyano-4-phenyl-6-aminopyridines and use thereof | BAYER HEALTHCARE AG (DE) | 2005-05-18 | — | — | CN | disclosed |
| EP-1455785-A1 | SUBSTITUTED 2-THIO-3,5-DICYANO-4-PHENYL-6-AMINOPYRIDINES AND THE USE OF THE SAME | Bayer HealthCare AG (DE) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053441-A1 | SUBSTITUTED 2-THIO-3,5-DICYANO-4-PHENYL-6-AMINOPYRIDINES AND THE USE OF THE SAME | BAYER HEALTHCARE AG (DE) | 2003-07-03 | — | — | WO | disclosed |
| EP-1059293-A1 | Novel amino chlorothiazole compounds | Microcide Pharmaceuticals, Inc. (US) | 2000-12-13 | — | — | EP | disclosed |
| EP-1059293-A1 | Novel amino chlorothiazole compounds | Microcide Pharmaceuticals, Inc. (US) | 2000-12-13 | — | — | EP | disclosed |