⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461605 | 0.71 | — | — | |
| SCHEMBL4422176 | 0.69 | — | — | |
| Bromide SCHEMBL19681460 | 0.69 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL643262 | 0.67 | — | — | |
| SCHEMBL7287966 | 0.67 | — | — | |
| SCHEMBL18569592 | 0.67 | — | — | |
| SCHEMBL1761114 | 0.67 | — | — | |
| Bromide SCHEMBL11344214 | 0.67 | — | — | |
| SCHEMBL10609050 | 0.67 | — | — | |
| SCHEMBL940050 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| US-9090601-B2 | Thiazole derivatives | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-07-28 | — | — | US | disclosed |
| US-20110003807-A1 | Thiazole derivatives | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | US | disclosed |