SCHEMBL4422188

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17737359	0.92	KMT2A (0.76)	KMT2AMEN1MAPK1HTTBLM
	SCHEMBL4422892	0.90	NPC1 (0.58)	KMT2AMEN1MAPK1HTTBLM
	SCHEMBL4424267	0.88	TRPV1 (0.60)	KMT2AMEN1MAPK1HTTBLM
	SCHEMBL3210996	0.87	TRPV1 (0.53)	KMT2AMEN1MAPK1HTTBLM
	SCHEMBL4433476	0.85	TRPV1 (0.65)	KMT2AMEN1MAPK1HTTBLM
	SCHEMBL13762081	0.83	TRPV1 (0.68)	KMT2AMEN1MAPK1HTTBLM
	SCHEMBL13544756	0.83	TRPV1 (0.74)	KMT2AMEN1MAPK1HTTBLM
	SCHEMBL11729390	0.82	KMT2A (0.72)	KMT2AMEN1MAPK1HTTBLM
	SCHEMBL26885232	0.81	NPC1 (0.81)	KMT2AMEN1TRPV1NPC1RAB9A
	SCHEMBL13763336	0.81	TRPV1 (0.60)	KMT2AMEN1MAPK1HTTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.