Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.78 |
| ▸ | MAOA | P21397 | 2/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.65 |
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306287 | 0.91 | MAOB (0.65) | MAOBMAOANR4A2PPARASLC16A3 | |
| SCHEMBL3296065 | 0.89 | MAOB (0.76) | MAOBMAOANR4A2PPARASLC16A3 | |
| SCHEMBL2997270 | 0.89 | MAOB (0.62) | MAOBMAOANR4A2SLC16A3PARP10 | |
| SCHEMBL3505716 | 0.88 | MAOB (0.74) | MAOBMAOANR4A2PARP10PARP15 | |
| Hydrochloric Acid SCHEMBL9015457 | 0.88 | MAOB (0.61) | MAOBMAOANR4A2SLC16A3PARP10 | |
| SCHEMBL10397844 | 0.87 | MAOB (0.64) | MAOBMAOANR4A2PPARASLC16A3 | |
| SCHEMBL4424324 | 0.85 | MAOB (0.59) | MAOBMAOANR4A2PPARA | |
| SCHEMBL7908630 | 0.85 | NR4A2 (0.60) | MAOBMAOANR4A2PPARASLC16A3 | |
| SCHEMBL4420072 | 0.84 | NR4A2 (0.59) | MAOBMAOANR4A2PPARASLC16A3 | |
| SCHEMBL31591512 | 0.84 | MAOB (0.61) | MAOBMAOANR4A2PPARASLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515926-B1 | FLUOROBENZAMIDES SUITABLE FOR THE TREATMENT OF ALZHEIMER'S DISEASE OR SENILE DEMENTIA | HOFFMANN LA ROCHE (CH) | 2009-04-08 | — | — | EP | disclosed |
| CN-1274669-C | Fluorobenzamides suitable for the treatment of alzheimer's disease or senile dementia | HOFFMANN LA ROCHE (CH) | 2006-09-13 | — | — | CN | disclosed |
| US-6951884-B2 | Fluorobenzamides and uses thereof | HOFFMANN-LA ROCHE INC. (US) | 2005-10-04 | — | — | US | disclosed |
| CN-1659135-A | Fluorobenzamides suitable for the treatment of alzheimer's disease or senile dementia | HOFFMANN LA ROCHE (CH) | 2005-08-24 | — | — | CN | disclosed |
| EP-1515926-A2 | FLUOROBENZAMIDES SUITABLE FOR THE TREATMENT OF ALZHEIMER'S DISEASE OR SENILE DEMENTIA | F.HOFFMANN-LA ROCHE AG (CH) | 2005-03-23 | — | — | EP | disclosed |
| US-20030236304-A1 | Fluorobenzamides and uses thereof | F. HOFFMANN-LA ROCHE AG (CH) | 2003-12-25 | — | — | US | disclosed |
| WO-2003106380-A2 | FLUOROBENZAMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236304-A1 | Fluorobenzamides and uses thereof | MAOB, MAOA, BCHE | MAOB 1/4885MAOA 2/4885NR4A2 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.