⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035603 | 0.85 | MEN1 (0.33) | — | |
| SCHEMBL7528758 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL30800371 | 0.72 | MEN1 (0.33) | — | |
| SCHEMBL6841561 | 0.72 | FFAR3 (0.33) | — | |
| SCHEMBL6841563 | 0.72 | FFAR3 (0.33) | — | |
| SCHEMBL19446690 | 0.68 | MME (0.32) | — | |
| SCHEMBL14631900 | 0.66 | LPAR1 (0.34) | — | |
| SCHEMBL552809 | 0.63 | TDP1 (0.38) | — | |
| SCHEMBL22644338 | 0.63 | — | — | |
| SCHEMBL14631781 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040094-B9 | SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARM INC (US) | 2015-09-09 | — | — | EP | disclosed |
| EP-1040094-B1 | SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARM INC (US) | 2009-03-18 | — | — | EP | disclosed |