Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 5/20 | 0.64 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 3/20 | 0.47 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3852211 | 0.92 | ITGA4 (0.61) | ITGA4ITGB1ITGB7ITGA5ALDH1A1 | |
| SCHEMBL3849600 | 0.91 | ITGA4 (0.61) | ITGA4ITGB1ITGB7ITGA5ALDH1A1 | |
| SCHEMBL4451795 | 0.91 | ITGA4 (0.56) | ITGA4ITGB1ITGB7ITGA5FKBP1A | |
| SCHEMBL4415640 | 0.91 | ITGA4 (0.59) | ITGA4ITGB1ITGB7ITGA5ALDH1A1 | |
| SCHEMBL4421854 | 0.89 | ITGA4 (0.58) | ITGA4ITGB1ITGB7ITGA5ALDH1A1 | |
| SCHEMBL3857243 | 0.88 | ITGA4 (0.58) | ITGA4ITGB1ITGB7ITGA5ALDH1A1 | |
| SCHEMBL3848377 | 0.88 | ITGA4 (0.60) | ITGA4ITGB1ITGB7ITGA5ALDH1A1 | |
| SCHEMBL3850695 | 0.88 | ITGA4 (0.58) | ITGA4ITGB1ITGB7ITGA5ALDH1A1 | |
| SCHEMBL3849687 | 0.88 | ITGA4 (0.58) | ITGA4ITGB1ITGB7ITGA5ALDH1A1 | |
| SCHEMBL4423030 | 0.88 | ITGA4 (0.58) | ITGA4ITGB1ITGB7ITGA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592387-A4 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARM INC (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1592387-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | Elan Pharmaceuticals, Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004066932-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARMACEUTICALS INC. (US) | 2004-08-12 | — | — | WO | disclosed |