Butane

Butane

SCHEMBL442322

CCCC.O=C(O)C=CC(=O)OCC1CO1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.53
MGLL Q99685 1/20 0.49
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL4901497 0.95 HCAR2 (0.53) HCAR2MGLLALDH1A1TP53CYP3A4
Ethane SCHEMBL2120677 0.93 MGLL (0.51) HCAR2MGLLALDH1A1TP53CYP3A4
SCHEMBL422857 0.93 MGLL (0.54) HCAR2MGLLALDH1A1TP53CYP3A4
SCHEMBL624268 0.93 MGLL (0.54) HCAR2MGLLALDH1A1TP53CYP3A4
SCHEMBL422856 0.93 MGLL (0.54) HCAR2MGLLALDH1A1TP53CYP3A4
Methane SCHEMBL7586475 0.91 MGLL (0.52) HCAR2MGLLALDH1A1TP53CYP3A4
Ether SCHEMBL9863201 0.90 HCAR2 (0.53) HCAR2MGLLALDH1A1TP53CYP3A4
Propene SCHEMBL10621329 0.89 MGLL (0.48) HCAR2MGLLALDH1A1TP53CYP3A4
SCHEMBL268635 0.86 MGLL (0.55) MGLLALDH1A1TP53CYP3A4
SCHEMBL268634 0.86 MGLL (0.55) MGLLALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2494562-B1 POSITIVE TEMPERATURE COEFFICIENT MATERIALS WITH REDUCED NEGATIVE TEMPERATURE COEFFICIENT EFFECT SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-05-30 EP disclosed
EP-2121840-B1 POLYCARBONATE/POLYOLEFIN BASED RESIN COMPOSITIONS AND THEIR PRODUCTION PROCESSES AND USES SABIC INNOVATIVE PLASTICS IP (NL) 2014-05-28 EP disclosed
EP-2365032-B1 Flame retardant flexible thermoplastic composition, method of making, and articles thereof SABIC INNOVATIVE PLASTICS IP (NL) 2014-05-07 EP disclosed
US-8496854-B2 Positive temperature coefficient materials with reduced negative temperature coefficient effect SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-07-30 US disclosed
US-8314181-B2 Polycarbonate/polyolefin based resin compositions and their production processes and uses SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-11-20 US disclosed
US-8273825-B2 excellent wear properties; polyolefin has been modified with at least one functional group selected from a carboxyl, an acid anhydride, an epoxy groups or mixtures; automotive parts to electronic appliances SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-09-25 US disclosed
EP-2494562-A1 POSITIVE TEMPERATURE COEFFICIENT MATERIALS WITH REDUCED NEGATIVE TEMPERATURE COEFFICIENT EFFECT SABIC Innovative Plastics IP B.V. (NL) 2012-09-05 EP disclosed
US-20120061120-A1 FLAME RETARDANT FLEXIBLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-03-15 US disclosed
US-20120010365-A1 POLYCARBONATE/POLYOLEFIN BASED RESIN COMPOSITIONS AND THEIR PRODUCTION PROCESSES AND USES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-01-12 US disclosed
US-20110297891-A1 POSITIVE TEMPERATURE COEFFICIENT MATERIALS WITH REDUCED NEGATIVE TEMPERATURE COEFFICIENT EFFECT SABIC INNOVATIVE PLASTICS IP B.V. (US) 2011-12-08 US disclosed
US-5360866-A With graft polypropylene MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1994-11-01 US disclosed
EP-0616013-A2 Thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1994-09-21 EP disclosed
EP-0572919-A1 Thermoplastic resin composition and process for preparing the same MITSUBISHI CHEMICAL CORPORATION (JP) 1993-12-08 EP disclosed
US-5244983-A Hydroxyalkylated, saturated polyester MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-09-14 US disclosed
US-5202409-A POLYHYDROXYPHENYLENE ETHER RESIN AND PROCESS FOR PREPARING THE SAME MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-04-13 US disclosed
EP-0268981-B1 THERMOPLASTIC RESIN COMPOSITION MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-09-30 EP disclosed
EP-0488381-A1 Polyhydroxyphenylene ether resin and process for preparing the same MITSUBISHI CHEMICAL CORPORATION (JP) 1992-06-03 EP disclosed
EP-0467261-A2 Thermoplastic polyphenylene ether resin composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1992-01-22 EP disclosed
US-4885334-A POLYPHENYLENE ETHER, POLAR THERMOPLASTIC RESIN, AROMATIC VINYL COMPOUND-CONJUGATED DIENE BLOCK POLYMER MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-12-05 US disclosed
EP-0268981-A2 Thermoplastic resin composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-06-01 EP disclosed