Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23613050 | 0.69 | NOTUM (0.50) | NOTUMALDH1A1MAPTMEN1LMNA | |
| SCHEMBL10222505 | 0.69 | NOTUM (0.50) | NOTUMALDH1A1MAPTMEN1LMNA | |
| SCHEMBL15458873 | 0.69 | NOTUM (0.50) | NOTUMALDH1A1MAPTMEN1LMNA | |
| SCHEMBL18977039 | 0.68 | PKM (0.43) | NOTUMALDH1A1NPSR1DRD2DRD4 | |
| SCHEMBL8366931 | 0.63 | CHRM2 (0.59) | NOTUMALDH1A1MAPTMEN1LMNA | |
| SCHEMBL22292629 | 0.62 | NOTUM (0.53) | NOTUMALDH1A1MAPTMEN1LMNA | |
| Hydrochloric Acid SCHEMBL5367455 | 0.62 | CHRM2 (0.57) | NOTUMALDH1A1NPSR1MAPTMEN1 | |
| SCHEMBL11348379 | 0.61 | CHRM2 (0.50) | NOTUMALDH1A1NPSR1DRD2MAPT | |
| SCHEMBL11995384 | 0.60 | CHRM2 (0.52) | NOTUMALDH1A1NPSR1MAPTMEN1 | |
| SCHEMBL2632947 | 0.60 | CHRM2 (0.52) | NOTUMALDH1A1NPSR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756096-B1 | INDOLYL DERIVATIVES AS LIVER-X-RECEPTOR MODULATORS | HOFFMANN LA ROCHE (CH) | 2009-08-12 | — | — | EP | disclosed |