SCHEMBL4423313

SCHEMBL4423313

O=[N+]([O-])C([C](O)C(c1ccccc1)[N+](=O)[O-])c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.44
LMNA P02545 3/20 0.41
ALDH1A1 P00352 1/20 0.41
SRC P12931 2/20 0.39
CYP2D6 P10635 1/20 0.39
ACP3 P15309 1/20 0.39
MAPK1 P28482 1/20 0.38
NPC1 O15118 1/20 0.38
ADAM17 P78536 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74691 0.84 SRC (0.48) GSRLMNAALDH1A1SRCCYP2D6
SCHEMBL9893480 0.83 GSR (0.42) GSRLMNAALDH1A1SRCCYP2D6
SCHEMBL31314504 0.83 GSR (0.42) GSRLMNAALDH1A1SRCCYP2D6
SCHEMBL11602886 0.83 SRC (0.46) GSRLMNAALDH1A1SRCCYP2D6
SCHEMBL5692151 0.83 GSR (0.42) GSRLMNAALDH1A1SRCCYP2D6
SCHEMBL11602507 0.83 SRC (0.46) GSRLMNAALDH1A1SRCCYP2D6
SCHEMBL887039 0.83 SRC (0.46) GSRLMNAALDH1A1SRCCYP2D6
SCHEMBL1538911 0.83 CES2 (0.43) GSRLMNAALDH1A1SRCCYP2D6
SCHEMBL7426840 0.81 GSR (0.41) GSRLMNAALDH1A1SRCCYP2D6
SCHEMBL11602890 0.81 GSR (0.41) GSRLMNAALDH1A1SRCCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10294526-B2 Polymer co-location in surface-attached biopolymers and arrays of biopolymers INTEL CORPORATION (US) 2019-05-21 US disclosed
US-20170356044-A1 POLYMER CO-LOCATION IN SURFACE-ATTACHED BIOPOLYMERS AND ARRAYS OF BIOPOLYMERS INTEL CORP (US) 2017-12-14 US disclosed
US-9745628-B2 Polymer co-location in surface-attached biopolymers and arrays of biopolymers INTEL CORPORATION (US) 2017-08-29 US disclosed
US-20140213484-A1 POLYMER CO-LOCATION IN SURFACE-ATTACHED BIOPOLYMERS AND ARRAYS OF BIOPOLYMERS INTEL CORPORATION 2014-07-31 US disclosed
US-8697605-B2 Polymer co-location in surface-attached biopolymers and arrays of biopolymers INTEL CORPORATION (US) 2014-04-15 US disclosed
US-20090325817-A1 Polymer co-location in surface-attached biopolymers and arrays of biopolymers INTEL CORPORATION 2009-12-31 US disclosed