SCHEMBL4423459

SCHEMBL4423459

CONOC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6840593 0.83
SCHEMBL31661041 0.80 ALDH1A1 (0.50)
SCHEMBL28481681 0.77
SCHEMBL7469646 0.75
Acetic Acid SCHEMBL7704494 0.73
Acetic Acid Methyl Ester SCHEMBL8322448 0.71 ALDH1A1 (1.00)
Acetic Acid Methyl Ester SCHEMBL28296965 0.71 ALDH1A1 (1.00)
Acetic Acid Methyl Ester SCHEMBL3080739 0.71
Acetic Acid Methyl Ester SCHEMBL3650 0.71
SCHEMBL6924582 0.71 HCAR2 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372363-B Preparation method of descarbamoyl cefuroxime 广东立国制药有限公司 2022-11-25 CN claimed
CN-113372363-A Preparation method of descarbamoyl cefuroxime 深圳市立国药物研究有限公司 2021-09-10 CN claimed
CN-112409206-B Preparation method of kresoxim-methyl 新发药业有限公司 2023-04-07 CN disclosed
CN-113372363-B Preparation method of descarbamoyl cefuroxime 广东立国制药有限公司 2022-11-25 CN disclosed
CN-112409207-B Preparation method of dimoxystrobin 新发药业有限公司 2022-11-22 CN disclosed
CN-113372363-A Preparation method of descarbamoyl cefuroxime 深圳市立国药物研究有限公司 2021-09-10 CN disclosed
CN-112409207-A Preparation method of dimoxystrobin 新发药业有限公司 2021-02-26 CN disclosed
CN-112409206-A Preparation method of kresoxim-methyl 新发药业有限公司 2021-02-26 CN disclosed
US-8232254-B2 Colchicine glycosylated to include a sugar moiety on a methoxyamino-appended colchicine; cytolysis equivalent to paclitaxel and doxorubicin; stabilizers of tubulin formation; anticarcinogenic -arthritic agents; Mediterranean fever, amyloidosis, scleroderma, irritable bowel syndrome or gout WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-07-31 US disclosed
US-20110256406-A1 Laser Weldable Thermoplastic Polyester Composition SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-10-20 US disclosed
EP-2076525-A2 COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE Wisconsin Alumni Research Foundation (US) 2009-07-08 EP disclosed
WO-2008067039-A9 COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE WISCONSIN ALUMNI RES FOUND (US) 2008-10-16 WO disclosed
US-20080171787-A1 COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-07-17 US disclosed
WO-2008067039-A2 COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-06-05 WO disclosed