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SCHEMBL4423642

SCHEMBL4423642

CC(CCNC(=O)OC(c1ccc(C(=O)C(C)(C)O)cc1)c1ccc(C(=O)C(C)(C)O)cc1)CC(C)(C)CNC(=O)OC(c1ccc(C(=O)C(C)(C)O)cc1)c1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4423646 0.83 — —
SCHEMBL3673808 0.83 SLC1A3 (0.37) SMN1; SMN2
SCHEMBL3087208 0.82 MLYCD (0.40) SMN1; SMN2
SCHEMBL3096274 0.82 MLYCD (0.40) SMN1; SMN2
SCHEMBL3076985 0.82 MLYCD (0.40) SMN1; SMN2
SCHEMBL4423648 0.80 KDM4E (0.31) SMN1; SMN2
SCHEMBL4414431 0.78 MLYCD (0.48) SMN1; SMN2
SCHEMBL27978002 0.78 MLYCD (0.37) SMN1; SMN2
SCHEMBL4417610 0.78 MLYCD (0.48) SMN1; SMN2
SCHEMBL27977983 0.78 MLYCD (0.37) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620475-B1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2009-11-11 — — EP disclosed
US-7462650-B2 Trifunctional photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-12-09 — — US disclosed
US-20060270748-A1 Novel trifunctional photoinitiators IGM GROUP B.V. (NL) 2006-11-30 — — US disclosed
EP-1620475-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS Ciba SC Holding AG (CH) 2006-02-01 — — EP disclosed
WO-2004099262-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-11-18 — — WO disclosed