Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333923 | 1.00 | CA2 (0.45) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL1120219 | 0.83 | CA1 (0.44) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL1120216 | 0.83 | CA1 (0.44) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL513627 | 0.74 | PPARG (0.47) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL513626 | 0.74 | PPARG (0.47) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL5973925 | 0.74 | PPARG (0.47) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL4632246 | 0.73 | CA2 (0.46) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL4632241 | 0.73 | CA2 (0.46) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL9598177 | 0.73 | CA1 (0.46) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL7119214 | 0.73 | CA2 (0.54) | CA2CA1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019819-A1 | NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS | Neobiotics AB (SE) | 2009-02-04 | — | — | EP | disclosed |
| WO-2007129952-A1 | NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS | NEOBIOTICS AB (SE) | 2007-11-15 | — | — | WO | disclosed |