Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.49 |
| ▸ | PGR | P06401 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424519 | 0.95 | IL6 (0.52) | IL6PGRKDM4EMEN1ALDH1A1 | |
| SCHEMBL2393354 | 0.92 | IL6 (0.52) | IL6PGRKDM4EMEN1ALDH1A1 | |
| SCHEMBL1315673 | 0.91 | IL6 (0.49) | IL6PGRKDM4EMEN1ALDH1A1 | |
| SCHEMBL5035554 | 0.90 | IL6 (0.55) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL17676715 | 0.90 | IL6 (0.51) | IL6PGRKDM4EMEN1ALDH1A1 | |
| SCHEMBL2395549 | 0.89 | IL6 (0.50) | IL6PGRKDM4EMEN1ALDH1A1 | |
| SCHEMBL2393287 | 0.89 | IL6 (0.49) | IL6PGRKDM4EMEN1ALDH1A1 | |
| SCHEMBL2391824 | 0.89 | IL6 (0.48) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL2393957 | 0.89 | IL6 (0.48) | IL6PGRKDM4EMEN1ALDH1A1 | |
| SCHEMBL2397683 | 0.89 | IL6 (0.48) | IL6PGRKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085387-B1 | NOVEL 1,2-DIHYDROQUINOLINE DERIVATIVE HAVING SUBSTITUTED PHENYLCHALCOGENO LOWER ALKYL GROUP AND ESTER-INTRODUCED PHENYL GROUP AS SUBSTITUENTS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2013-04-10 | — | — | EP | disclosed |
| EP-2085387-A1 | NOVEL 1,2-DIHYDROQUINOLINE DERIVATIVE HAVING SUBSTITUTED PHENYLCHALCOGENO LOWER ALKYL GROUP AND ESTER-INTRODUCED PHENYL GROUP AS SUBSTITUENTS | Santen Pharmaceutical Co., Ltd (JP) | 2009-08-05 | — | — | EP | disclosed |