Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4421084 | 0.94 | POLB (0.40) | POLBGAA | |
| SCHEMBL4424406 | 0.93 | MAPT (0.43) | POLBMAPTGAA | |
| SCHEMBL4426539 | 0.92 | MEN1 (0.44) | MAPTALDH1A1 | |
| SCHEMBL4434706 | 0.89 | POLB (0.37) | POLBMAPTALDH1A1LMNAGAA | |
| SCHEMBL4434995 | 0.88 | MAPT (0.44) | POLBMAPTLMNA | |
| SCHEMBL4426464 | 0.85 | GAA (0.36) | POLBALDH1A1LMNAGAAKDM4E | |
| SCHEMBL27412073 | 0.83 | POLB (0.41) | POLBMAPT | |
| SCHEMBL4425759 | 0.81 | POLB (0.51) | POLBMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL4426625 | 0.81 | ACP3 (0.36) | — | |
| SCHEMBL4425137 | 0.81 | MAPT (0.49) | POLBMAPTALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638505-B2 | Organophosphoric derivatives useful as anti-parasitic agents | UNIVERSITEIT GENT (BE) | 2009-12-29 | — | — | US | disclosed |
| US-20080312190-A1 | Such as 3-(N-hydroxyacetamido)-1-(3,4-dichlorophenyl)propylphosphonic acid; Antimalaria agents | UNIVERSITEIT GENT (BE) | 2008-12-18 | — | — | US | disclosed |
| WO-2005048715-A2 | ORGANOPHOSPHORIC COMPOUNDS AND USE THEREOF | BIOAGENCY AG (DE) | 2005-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312190-A1 | Such as 3-(N-hydroxyacetamido)-1-(3,4-dichlorophenyl)propylphosphonic acid; Antimalaria agents | SUB1, CBR1, NAT1 | POLB 1824/4885MAPT 4756/4885ALDH1A1 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.