Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27412073 | 0.94 | POLB (0.41) | MAPTPOLB | |
| SCHEMBL27411077 | 0.91 | POLB (0.39) | MAPTPOLB | |
| SCHEMBL4424406 | 0.89 | MAPT (0.43) | MAPTPOLB | |
| SCHEMBL27410888 | 0.88 | — | — | |
| SCHEMBL4423933 | 0.88 | POLB (0.45) | MAPTPOLBLMNA | |
| SCHEMBL27411084 | 0.86 | POLB (0.37) | MAPTPOLB | |
| SCHEMBL4421084 | 0.86 | POLB (0.40) | POLB | |
| SCHEMBL4426539 | 0.84 | MEN1 (0.44) | MAPT | |
| SCHEMBL27411088 | 0.84 | POLB (0.33) | MAPTPOLB | |
| SCHEMBL4435048 | 0.83 | MAPT (0.40) | MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217997-A1 | NOVEL MEPICIDES AS ANTIMICROBIAL AGENTS | GEORGE MASON UNIVERSITY | 2024-07-04 | — | — | US | disclosed |
| US-7638505-B2 | Organophosphoric derivatives useful as anti-parasitic agents | UNIVERSITEIT GENT (BE) | 2009-12-29 | — | — | US | disclosed |
| US-20080312190-A1 | Such as 3-(N-hydroxyacetamido)-1-(3,4-dichlorophenyl)propylphosphonic acid; Antimalaria agents | UNIVERSITEIT GENT (BE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217997-A1 | NOVEL MEPICIDES AS ANTIMICROBIAL AGENTS | SMPD1, MLYCD, SMPD3 | MAPT 4119/4885POLB 994/4885LMNA 3917/4885 |
| US-20080312190-A1 | Such as 3-(N-hydroxyacetamido)-1-(3,4-dichlorophenyl)propylphosphonic acid; Antimalaria agents | SUB1, CBR1, NAT1 | MAPT 4756/4885POLB 1824/4885LMNA 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.